Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
MORPHOLOGICAL FEATURES OF THE RETINAL-PIGMENT EPITHELIUM IN THE TOAD,BUFO-MARINUS
Autore:
SULEIMAN J; MONAIM MMA; ASHRAF M;
Indirizzi:
UNIV CINCINNATI,COLL MED,DEPT PATHOL,231 BETHESDA AVE CINCINNATI OH 45267 UNIV CINCINNATI,MED CTR,DEPT PATHOL & LAB MED CINCINNATI OH 45267 UNIV CINCINNATI,MED CTR,DEPT ANAT CINCINNATI OH 45267
Titolo Testata:
The Anatomical record
fascicolo: 1, volume: 249, anno: 1997,
pagine: 128 - 134
SICI:
0003-276X(1997)249:1<128:MFOTRE>2.0.ZU;2-B
Fonte:
ISI
Lingua:
ENG
Soggetto:
FINE-STRUCTURE;
Keywords:
MICROSCOPY; RETINAL PIGMENT EPITHELIUM; TOAD;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
22
Recensione:
Indirizzi per estratti:
Citazione:
J. Suleiman et al., "MORPHOLOGICAL FEATURES OF THE RETINAL-PIGMENT EPITHELIUM IN THE TOAD,BUFO-MARINUS", The Anatomical record, 249(1), 1997, pp. 128-134

Abstract

Background: The toad's (Bufo marinus) retinal pigment epithelium (RPE) has been used in many studies as a model for understanding its role and interaction with the neural retina (NR), In this study, the fine structure of the RPE is described, Methods: In vitro RPE-chorion preparations from the toad were studied after separation from the NR. Tissues were processed for light and electron microscopy. Results: The RPE consists of a single layer of cells joined by a series of tight junctions forming part of the blood-retina barrier. These cells had minimal infolding of the basal membrane and numerous microvillous processes extending from the apical surface and surrounding photoreceptor outer segments, Internally, RPE cells display a large nucleus, numerous mitochondria located at the basal membrane, extensive smooth endoplasmic reticulum, myeloid bodies, phagosomes, scattered polysomes, large lipid droplets and melanin granules, Rough endoplasmic reticulum is relativelyscarce within these cells, The choriocapillaris consists of large blood vessels facing Bruch's membrane, Bruch's membrane is typical of other vertebrates, being pentalaminate over the whole retina. The endothelium of the choriocapillaris facing Bruch's membrane is typically verythin but shows few fenestrations, Conclusions: Due to the ultrastructural similarities of toad RPE with that of mammals, it can serve as anexcellent model for the study of retinal detachment/reattachment and their cellular and molecular mechanisms. (C) 1997 Wiley-Liss, Inc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/03/20 alle ore 11:09:02