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Titolo:
SONOGRAPHIC BLOOD-FLOW MEASUREMENTS IN MALIGNANT BREAST-TUMORS - A POTENTIAL NEW PROGNOSTIC FACTOR
Autore:
SOHN C; BELDERMANN F; BASTERT G;
Indirizzi:
UNIV HEIDELBERG,FRAUENKLIN,VOSS STR 9 D-69115 HEIDELBERG GERMANY UNIV HEIDELBERG,DEPT PRENATAL & GYNECOL ULTRASOUND DIAG & TREATME,CLIN OB GYN HEIDELBERG GERMANY
Titolo Testata:
Surgical endoscopy
fascicolo: 9, volume: 11, anno: 1997,
pagine: 957 - 960
SICI:
0930-2794(1997)11:9<957:SBMIMB>2.0.ZU;2-U
Fonte:
ISI
Lingua:
ENG
Keywords:
ULTRASOUND BLOOD FLOW; MEM TECHNIQUE; PRONOSTIC FACTORS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
16
Recensione:
Indirizzi per estratti:
Citazione:
C. Sohn et al., "SONOGRAPHIC BLOOD-FLOW MEASUREMENTS IN MALIGNANT BREAST-TUMORS - A POTENTIAL NEW PROGNOSTIC FACTOR", Surgical endoscopy, 11(9), 1997, pp. 957-960

Abstract

Background: The aim of this study was to find a possible relationshipbetween the biological behavior of carcinomas of the breast and sonographically detectable blood flow after first studies showed a correlation between blood flow and prognostic factors. Method: 259 patients with ductal invasive breast cancer were examined using MEM (i.e., the Maximum Entropy Method), a new sonographic blood flow measurement technique capable of discerning considerably slower blood flow velocities than Doppler sonography. Due to the lack of objective methods for quantifying the blood flow, the findings were divided into three classes dependent upon the visual color information obtained. The blood flow was correlated with the size of the tumor, lymph node and receptor status,ploidy and S-phase fraction. Results: Most of the patients with smalltumors, without lymph node metastases, with positive receptors, with a diploid genome, and with a low S-phase fraction belonged to the group with the lowest blood flow. Conclusion: The close relationship between the established prognostic factors and the sonographic blood flow measurements using MEM might be indicative of a new preoperative prognostic factor; this must, however, be confirmed by larger studies.

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Documento generato il 11/07/20 alle ore 04:47:03