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Titolo:
PLACENTAL GLUCOSE TRANSPORTERS IN FETAL INTRAUTERINE GROWTH-RETARDATION AND MACROSOMIA
Autore:
KAINULAINEN H; JARVINEN T; HEINONEN PK;
Indirizzi:
UNIV TAMPERE,INST MED TECHNOL,POB 607 FIN-33101 TAMPERE FINLAND TAMPERE UNIV HOSP,DEPT OBSTET & GYNECOL TAMPERE FINLAND UNIV TAMPERE,SCH MED FIN-33101 TAMPERE FINLAND
Titolo Testata:
Gynecologic and obstetric investigation
fascicolo: 2, volume: 44, anno: 1997,
pagine: 89 - 92
SICI:
0378-7346(1997)44:2<89:PGTIFI>2.0.ZU;2-0
Fonte:
ISI
Lingua:
ENG
Soggetto:
DIABETIC RATS; METABOLISM; EXPRESSION; PROTEIN; LOCALIZATION; PREGNANCY;
Keywords:
GLUCOSE TRANSPORTERS; INTRAUTERINE GROWTH RETARDATION; MACROSOMIA; MATERNAL DIABETES MELLITUS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
21
Recensione:
Indirizzi per estratti:
Citazione:
H. Kainulainen et al., "PLACENTAL GLUCOSE TRANSPORTERS IN FETAL INTRAUTERINE GROWTH-RETARDATION AND MACROSOMIA", Gynecologic and obstetric investigation, 44(2), 1997, pp. 89-92

Abstract

To investigate the role of placental glucose delivery in fetal growth, two glucose transporters (Glut3 and Glut4) were determined from termplacentae. This was accomplished by immunoblotting from crude placental membrane samples from cases of fetal intrauterine growth retardation (IUGR, n = 6), macrosomia (n = 6), maternal diabetes mellitus (n = 4) and normal term (n = 8). Glut3 and Glut4 were detected in only very low numbers in all patient groups and there were no changes in their placental density, which suggests that the expression of these transporters is not involved in disorders of fetal growth. However, birth weight corresponded to placental weight, indicating that the total amount of Glut3 and Glut4 is reduced in IUGR and increased in macrosomia.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 21/09/20 alle ore 06:22:09