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Titolo:
INCIDENCE OF MALIGNANT PLEURAL MESOTHELIOMA AFTER THORACIC RADIOTHERAPY
Autore:
NEUGUT AI; AHSAN H; ANTMAN KH;
Indirizzi:
COLUMBIA PRESBYTERIAN MED CTR,DIV ONCOL,630 W 168TH ST NEW YORK NY 10032 COLUMBIA UNIV,COLL PHYS & SURG,DEPT MED NEW YORK NY 00000 COLUMBIA UNIV,COLL PHYS & SURG,SCH PUBL HLTH NEW YORK NY 00000
Titolo Testata:
Cancer
fascicolo: 5, volume: 80, anno: 1997,
pagine: 948 - 950
SICI:
0008-543X(1997)80:5<948:IOMPMA>2.0.ZU;2-W
Fonte:
ISI
Lingua:
ENG
Soggetto:
BREAST-CANCER; RADIATION-THERAPY; LUNG-CANCER; RISK;
Keywords:
MESOTHELIOMA; BREAST CARCINOMA; HODGKINS DISEASE; RADIOTHERAPY; RADIATION EFFECT; ETIOLOGY; 2ND NEOPLASMS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
25
Recensione:
Indirizzi per estratti:
Citazione:
A.I. Neugut et al., "INCIDENCE OF MALIGNANT PLEURAL MESOTHELIOMA AFTER THORACIC RADIOTHERAPY", Cancer, 80(5), 1997, pp. 948-950

Abstract

BACKGROUND. Although usually associated with asbestos exposure, a number of case reports have noted the occurrence of malignant pleural mesothelioma in patients who received radiotherapy (RT) to the thorax. METHODS. The authors performed a retrospective cohort study utilizing 251,750 women registered with breast carcinoma in the Surveillance, Epidemiology: and End Results Program of the U.S. National Cancer Institute from 1973-1993, 24.8% of whom received RT as parr of their initial management, and 13,743 people with Hodgkin's disease, 50.6% of whom received RT as part of their initial management. RESULTS. Six cases of malignant pleural mesothelioma were found: two in breast carcinoma patients treated with RT and four found in women not treated with RT. No cases occurred in the patients with Hodgkin's disease. The overall estimated relative risk for malignant pleural mesothelioma after RT was 1.56 (95% confidence interval, 0.18-5.63). CONCLUSIONS. To the authors' knowledge, this is the first controlled study to investigate thoracic radiation exposure and malignant pleural mesothelioma, and no association was found. (C) 1997 American Cancer Society.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 03/12/20 alle ore 12:48:02