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Titolo:
SIMULTANEOUS DETERMINATION OF ANIONS AND TRICLOSAN IN DENTIFRICES BY GRADIENT ION CHROMATOGRAPHY AND ISOCRATIC HIGHPERFORMANCE LIQUID-CHROMATOGRAPHY INTERFACED WITH CONDUCTIVITY AND ULTRAVIOLET DETECTION
Autore:
DEMKOWICZ MP; CHAUHAN V; STERN DA; VASQUEZ FG;
Indirizzi:
SMITHKLINE BEECHAM CONSUMER BRANDS,ANALYT MICROBIOL RES DEPT PARSIPPANY NJ 07054
Titolo Testata:
Journal of chromatography
fascicolo: 1-2, volume: 671, anno: 1994,
pagine: 351 - 357
Fonte:
ISI
Lingua:
ENG
Soggetto:
2-DIMENSIONAL CONDUCTOMETRIC DETECTION; POSTSUPPRESSOR CONVERSION; ELUITE ACIDS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
13
Recensione:
Indirizzi per estratti:
Citazione:
M.P. Demkowicz et al., "SIMULTANEOUS DETERMINATION OF ANIONS AND TRICLOSAN IN DENTIFRICES BY GRADIENT ION CHROMATOGRAPHY AND ISOCRATIC HIGHPERFORMANCE LIQUID-CHROMATOGRAPHY INTERFACED WITH CONDUCTIVITY AND ULTRAVIOLET DETECTION", Journal of chromatography, 671(1-2), 1994, pp. 351-357

Abstract

The simultaneous separation of fluoride, phosphates and triclosan ions (F-, PO43-, P2O74-, Cl2H7C13O2) in a dentifrice formulation using a coupled ion chromatography and high-performance liquid chromatography system is described. The anion species are separated from the other components of a given dentifrice formulation using a Dionex IonPac AS11 (250 x 4.0 mm) analytical column. A sodium hydroxide (200 mM to 100% water) gradient mobile phase is used to elute the fluoride and phosphate species from the column within 7 min using a Dionex Anion Self-Regenerating Suppressor (ASRS-I 4 mm). The separation of anions and triclosan was carried out using a two-mobile phase system that simultaneouslyinjected a 15-mu l sample into the 200 mM NaOH to 100% water ion chromatography gradient system as well as a 10-mu l sample into the water-acetonitrile (40:60) isocratic HPLC system. The anion species are thenquantitated using a conductometric detector (0-30 CLS). Triclosan is separated from the other components of the dentifrice formulation using a Waters Nova-Pak C-18, 4 mu m, 150 x 3.9 mm HPLC column. A water-acetonitrile (40:60) mobile phase is used to elute the triclosan from the column within 6 min. The triclosan analyte is then quantitated usingultraviolet detection at 280 nm and 0.005 AUFS. All analytes are quantitated using the Dionex AI-450 chromatography software program (release 3.30).

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/11/20 alle ore 17:11:42