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Titolo:
DETECTION OF RESIDUAL TUMORS IN POSTCHEMOTHERAPY TESTICULAR CANCER BYFDG-PET
Autore:
NUUTINEN JM; LESKINEN S; ELOMAA I; MINN H; VARPULA M; SOLIN O; SODERSTROM KO; JOENSUU H; SALMINEN E;
Indirizzi:
UNIV TURKU,DEPT RADIOTHERAPY & ONCOL FIN-20520 TURKU FINLAND TURKU PET CTR FIN-20520 TURKU FINLAND UNIV HELSINKI,DEPT ONCOL FIN-00290 HELSINKI FINLAND UNIV TURKU,MED IMAGING CTR FIN-20520 TURKU FINLAND ABO AKAD UNIV,ACCELERATOR LAB SF-20500 TURKU FINLAND UNIV TURKU,DEPT PATHOL FIN-20520 TURKU FINLAND
Titolo Testata:
European journal of cancer
fascicolo: 8, volume: 33, anno: 1997,
pagine: 1234 - 1241
SICI:
0959-8049(1997)33:8<1234:DORTIP>2.0.ZU;2-6
Fonte:
ISI
Lingua:
ENG
Soggetto:
GERM-CELL TUMORS; POSITRON EMISSION TOMOGRAPHY; FLUORINE-18-FLUORODEOXYGLUCOSE; CHEMOTHERAPY; RECURRENCE; MANAGEMENT; THERAPY;
Keywords:
POSITRON EMISSION TOMOGRAPHY; FLUORODEOXYGLUCOSE; TESTICULAR CANCER; RESIDUAL TUMOR;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
28
Recensione:
Indirizzi per estratti:
Citazione:
J.M. Nuutinen et al., "DETECTION OF RESIDUAL TUMORS IN POSTCHEMOTHERAPY TESTICULAR CANCER BYFDG-PET", European journal of cancer, 33(8), 1997, pp. 1234-1241

Abstract

The aim of this study was to investigate whether 2-(F-18)-fluoro-2-deoxy-D-glucose-positron emission tomography (FDG-PET) could reliably detect testicular cancer in patients following chemotherapy. Twenty FDG-PET studies were performed on 15 patients with metastatic seminoma or non-seminoma. Tracer uptake in the PET study was measured by calculating the standardised uptake value (SUV) for the tracer. Nine lesions out of 20 were judged to be positive based on high FDG uptake. Three proved to represent inflammatory changes in non-cancerous tissue. Eleven PET studies were negative. In one of these, viable tumour was found atretroperitoneal lymphadenectomy. The median SUV values of metastatic tumours and benign residual tumours were 2.7 (range 1.6-9.5, n = 10) and 1.7 (range 0.7-5.5, n = 15), respectively. The large overlap of SUVs between these groups was due to the relatively high FDG uptake in inflammatory tissue (median 4.2, range 2.0-5.5, n = 4). The results indicate that FDG imaging of metastatic testicular cancer after chemotherapy has limited value because of a potentially high accumulation of FDGin inflammatory tissues. (C) 1997 Published by Elsevier Science Ltd.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/03/20 alle ore 09:30:10