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Titolo:
HYALINE-MEMBRANE DISEASE (HMD) THERAPY IN LATIN-AMERICA - IMPACT OF EXOGENOUS SURFACTANT ADMINISTRATION ON NEW BORN SURVIVAL, MORBIDITY ANDUSE OF RESOURCES
Autore:
ROSSELLO JD; HAYWARD PE; MARTELL M; DELBARCO M; MARGOTTO P; GRANDZOTO J; BASTIDA J; PENA J; VILLANUEVA D;
Indirizzi:
CLAP PAHO WHO,CASILLA CORREO 627 MONTEVIDEO 11600 URUGUAY CLAP PAHO WHO MONTEVIDEO 11600 URUGUAY HOSP MATERNO INFANTIL SALTA SALTA ARGENTINA HOSP MATERNIDAD L2 SUL BRASILIA BRASILIA DF BRAZIL UNIV FED PELOTAS PELOTAS BRAZIL UNIV VALLE CALI CALI COLOMBIA UNIV REPUBLICA,DEPT NEONATOL MONTEVIDEO URUGUAY HOSP INFANTIL MEXICO DR FEDERICO GOMEZ MEXICO CITY DF MEXICO
Titolo Testata:
Journal of perinatal medicine
fascicolo: 3, volume: 25, anno: 1997,
pagine: 280 - 287
SICI:
0300-5577(1997)25:3<280:HD(TIL>2.0.ZU;2-K
Fonte:
ISI
Lingua:
ENG
Soggetto:
RESPIRATORY-DISTRESS SYNDROME; SYNTHETIC SURFACTANT; INFANTS; MORTALITY;
Keywords:
HYALINE MEMBRANE DISEASE; LATIN AMERICA; NEWBORN; PULMONARY SURFACTANTS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
8
Recensione:
Indirizzi per estratti:
Citazione:
J.D. Rossello et al., "HYALINE-MEMBRANE DISEASE (HMD) THERAPY IN LATIN-AMERICA - IMPACT OF EXOGENOUS SURFACTANT ADMINISTRATION ON NEW BORN SURVIVAL, MORBIDITY ANDUSE OF RESOURCES", Journal of perinatal medicine, 25(3), 1997, pp. 280-287

Abstract

Impact of surfactant administration, on neonatal mortality, morbidityand resource use, was assayed in a historically controlled study in 19 NICUs from 5 Latin American countries. Data from clinical records ofinfants with HMD were retrospectively reviewed for the previous 2 years (PRE phase n = 666 cases), and prospectively in cases that receivedsurfactant (SURF phase, 348 cases). Birth weight stratified relative risk, with 95% confidence interval (RR +/-95% CI) for death, in the SURF as compared to the PRE was 0.60 (0.49-0.74), 0.79 (0.68-0.92) and 0.82 (0.71-0.94), for days 7, 28 and at discharge, respectively. At allages mortality was significantly lower during SURF. Significant increases were observed in the occurrence of pulmonary interstitial emphysema, pulmonary hemorrhage, patent ductus arteriosus, bronchopulmonary dysplasia, intrahospital infection and necrotizing enterocolitis. Resource use increased significantly. It is concluded that the use of surfactant in the region is an important advance, and the efficacy of management of the late complications of the very premature and labile HMD survivors must increase. More attention should be given to thermal regulation, nutrition and management of infection in the survivors, beforea more marked effect of surfactant can be seen.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 08/04/20 alle ore 09:02:38