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Titolo:
CATFISH THROMBOCYTES EXPRESS AN INTEGRIN-LIKE CD41 CD61 COMPLEX/
Autore:
PASSER BJ; CHEN CLH; MILLER NW; COOPER MD;
Indirizzi:
UNIV ALABAMA,DIV DEV & CLIN IMMUNOL,WALLACE TUMOR INST 378 BIRMINGHAMAL 35294 UNIV ALABAMA,DIV DEV & CLIN IMMUNOL,WALLACE TUMOR INST 378 BIRMINGHAMAL 35294 UNIV ALABAMA,DEPT MICROBIOL BIRMINGHAM AL 35294 UNIV ALABAMA,DEPT MED BIRMINGHAM AL 35294 UNIV ALABAMA,DEPT PEDIAT BIRMINGHAM AL 35294 UNIV ALABAMA,HOWARD HUGHES MED INST BIRMINGHAM AL 35294 UNIV MISSISSIPPI,MED CTR,DEPT MICROBIOL JACKSON MS 39216
Titolo Testata:
Experimental cell research
fascicolo: 2, volume: 234, anno: 1997,
pagine: 347 - 353
SICI:
0014-4827(1997)234:2<347:CTEAIC>2.0.ZU;2-N
Fonte:
ISI
Lingua:
ENG
Soggetto:
MEMBRANE GLYCOPROTEIN-IIB; CHANNEL CATFISH; FUNCTIONAL-CHARACTERIZATION; MONOCLONAL-ANTIBODIES; CHICKEN THROMBOCYTES; ICTALURUS-PUNCTATUS; ALPHA-SUBUNIT; IIIA COMPLEX; CELL-LINES; GPIIB-IIIA;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
42
Recensione:
Indirizzi per estratti:
Citazione:
B.J. Passer et al., "CATFISH THROMBOCYTES EXPRESS AN INTEGRIN-LIKE CD41 CD61 COMPLEX/", Experimental cell research, 234(2), 1997, pp. 347-353

Abstract

A thrombocyte-specific antigen was identified in two closely related catfish, Ictalurus punctatus and Ictalurus furcatus, by monoclonal antibodies 4-20 and 72. The antibodies immunoprecipitate two noncovalently associated glycoprotein chains of M-r 180,000 and M-r 95,000. Under reducing conditions the M-r 180,000 chain is resolved into M-r 150,000and 32,000 subcomponents. Analysis of N-terminal amino acid sequencesindicates homology of the M-r 95,000 chain with the PS integrin subunit and homology of the M-r 150,000 chain with the alpha(IIb) integrin subunit. These antibodies induce catfish thrombocyte aggregation and alteration of cell shape. The data indicate conservation of the megakaryocyte/platelet-restricted CD41/CD61 complex in bony fish. (C) 1997 Academic Press.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 31/03/20 alle ore 10:11:28