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Titolo:
NATURAL OCCURRENCE OF 2'-PHOSPHO-CYCLIC ADP RIBOSE IN MAMMALIAN-TISSUES
Autore:
VU CQ; COYLE DL; JACOBSON MK;
Indirizzi:
UNIV KENTUCKY,COLL PHARM,DIV MED CHEM & PHARMACEUT LEXINGTON KY 40526 UNIV KENTUCKY,COLL PHARM,DIV MED CHEM & PHARMACEUT LEXINGTON KY 40526 UNIV KENTUCKY,LUCILLE P MARKEY CANC CTR LEXINGTON KY 40526
Titolo Testata:
Biochemical and biophysical research communications
fascicolo: 3, volume: 236, anno: 1997,
pagine: 723 - 726
SICI:
0006-291X(1997)236:3<723:NOO2AR>2.0.ZU;2-4
Fonte:
ISI
Lingua:
ENG
Soggetto:
ISOLATED HEPATOCYTES; OXIDATIVE STRESS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Science Citation Index Expanded
Citazioni:
14
Recensione:
Indirizzi per estratti:
Citazione:
C.Q. Vu et al., "NATURAL OCCURRENCE OF 2'-PHOSPHO-CYCLIC ADP RIBOSE IN MAMMALIAN-TISSUES", Biochemical and biophysical research communications, 236(3), 1997, pp. 723-726

Abstract

2'-Phospho-cyclic ADP-ribose (P-cADPR) is a newly identified Ca2+-mobilizing agent derived from NADP that stimulates intracellular Ca2+ release by a mechanism distinct from inositol 1,4,5-trisphosphate. In this report, we show that P-cADPR is an endogenous metabolite in bovine tissues with basal levels ranging from 17.6 to 89.5 fmol/mg protein. The natural occurrence of this Ca2+-mobilizing nucleotide provides a potential link between NADP(H) metabolism and regulation of Ca2+ homeostasis. (C) 1997 Academic Press.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/10/20 alle ore 12:37:53