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Titolo:
ACTIVE AND PASSIVE SMOKING ARE ASSOCIATED WITH INCREASED CAROTID WALLTHICKNESS - THE ATHEROSCLEROSIS RISK IN COMMUNITIES STUDY
Autore:
HOWARD G; BURKE GL; SZKLO M; TELL GS; ECKFELDT J; EVANS G; HEISS G;
Indirizzi:
WAKE FOREST UNIV,BOWMAN GRAY SCH MED,DEPT PUBL HLTH SCI,MED CTR BLVD WINSTON SALEM NC 27157 WAKE FOREST UNIV,BOWMAN GRAY SCH MED,DEPT NEUROL WINSTON SALEM NC 27103 JOHNS HOPKINS UNIV,SCH HYG & PUBL HLTH BALTIMORE MD 00000 UNIV MINNESOTA,DEPT LAB MED & PATHOL MINNEAPOLIS MN 55455 UNIV N CAROLINA,SCH PUBL HLTH,DEPT EPIDEMIOL CHAPEL HILL NC 00000
Titolo Testata:
Archives of internal medicine
fascicolo: 11, volume: 154, anno: 1994,
pagine: 1277 - 1282
SICI:
0003-9926(1994)154:11<1277:AAPSAA>2.0.ZU;2-D
Fonte:
ISI
Lingua:
ENG
Soggetto:
CIGARETTE-SMOKING; ARTERY ATHEROSCLEROSIS; ULTRASOUND; DISEASE; PLASMA; LIPIDS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Science Citation Index Expanded
Citazioni:
23
Recensione:
Indirizzi per estratti:
Citazione:
G. Howard et al., "ACTIVE AND PASSIVE SMOKING ARE ASSOCIATED WITH INCREASED CAROTID WALLTHICKNESS - THE ATHEROSCLEROSIS RISK IN COMMUNITIES STUDY", Archives of internal medicine, 154(11), 1994, pp. 1277-1282

Abstract

Background: Active cigarette smoking has been established as a potentrisk factor for carotid atherosclerosis in clinical populations; however, neither the role of active smoking in general populations nor theimpact of environmental tobacco smoke has been well described. Methods: The association between carotid artery wall thickness and cigarettesmoking was studied in 12953 black and white men and women, aged 45 to 65 years, examined in the Atherosclerosis Risk in Communities Study. Participants were classified as current smokers (n=3525), past smokers (n=4315), never smokers reporting weekly exposure to environmental tobacco smoke (ETS or ''passive smoking'') of at least 1 hour (n=3339),or never smokers reporting no weekly exposure to ETS (n=1774). Carotid artery intimal-medial thickness (IMT) was measured by B-mode ultrasound. Results: Increased IMT was observed in each category, in order from smallest to greatest increase: never smokers not exposed to ETS, never smokers exposed to ETS, past smokers, and current smokers. The larger IMT observed in the nonsmoking group exposed to ETS compared with the nonsmokers not exposed persisted after control for diet, physical activity, body mass index, alcohol intake, education, and major cardiovascular risk factors. Among past and current smokers, increased pack-years of exposure was associated with increased IMT. Among nonsmoking men exposed to ETS, there was a significant increase in IMT with increasing number of hours per week of ETS exposure. Conclusions: These data confirm the strong relationship between active smoking and carotid artery IMT and provide initial evidence that passive smoking exposure is related to greater IMT. Increasing exposure to cigarette smoke (either pack-years of active smoking or hours of ETS) was significantly related to increased IMT.

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Documento generato il 04/12/20 alle ore 16:28:03