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Titolo:
Genotoxic response of Austrian groundwater samples treated under standardized UV (254 nm) - disinfection conditions in a combination of three different bioassays
Autore:
Haider, T; Sommer, R; Knasmuller, S; Eckl, P; Pribil, W; Cabaj, A; Kundi, M;
Indirizzi:
Univ Vienna, Inst Environm Hyg, A-1095 Vienna, Austria Univ Vienna Vienna Austria A-1095 t Environm Hyg, A-1095 Vienna, Austria Univ Vienna, Inst Hyg, Vienna, Austria Univ Vienna Vienna AustriaUniv Vienna, Inst Hyg, Vienna, Austria Univ Vienna, Inst Canc Res, Vienna, Austria Univ Vienna Vienna AustriaUniv Vienna, Inst Canc Res, Vienna, Austria Salzburg Univ, Inst Genet & Gen Biol, A-5020 Salzburg, Austria Salzburg Univ Salzburg Austria A-5020 Gen Biol, A-5020 Salzburg, Austria Univ Vet Med, Inst Med Phys, Vienna, Austria Univ Vet Med Vienna Austria niv Vet Med, Inst Med Phys, Vienna, Austria
Titolo Testata:
WATER RESEARCH
fascicolo: 1, volume: 36, anno: 2002,
pagine: 25 - 32
SICI:
0043-1354(200201)36:1<25:GROAGS>2.0.ZU;2-M
Fonte:
ISI
Lingua:
ENG
Soggetto:
HEPATOCYTE MICRONUCLEUS ASSAY; DRINKING-WATER; MUTAGENIC ACTIVITY; PLANT BIOASSAYS; TRADESCANTIA-MICRONUCLEUS; WASTE SITES; IRRADIATION; CLASTOGENICITY; NETHERLANDS; INDUCTION;
Keywords:
groundwater; UV (254nm) disinfection; mutagenicity; genotoxicity;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Agriculture,Biology & Environmental Sciences
Citazioni:
41
Recensione:
Indirizzi per estratti:
Indirizzo: Haider, T Univ Vienna, Inst Environm Hyg, Kinderspitalgasse 15, A-1095 Vienna, Austria Univ Vienna Kinderspitalgasse 15 Vienna Austria A-1095 Austria
Citazione:
T. Haider et al., "Genotoxic response of Austrian groundwater samples treated under standardized UV (254 nm) - disinfection conditions in a combination of three different bioassays", WATER RES, 36(1), 2002, pp. 25-32

Abstract

Ground water samples from different geographic areas in Austria, with different amounts of natural and anthropogenic organic compounds were treated with a standardized low pressure UV (254nm)-irradiation laboratory flow-through system (UV fluence: 800 J/m(2)). The genotoxic activities of the water samples before and after the UV disinfection were investigated using a combination of three different bioassays which complement each other with regard to their sensitivity detecting different genotoxins. The test battery comprises the Salmonella/microsome assay (Ames test with TA98, TA 100 and TA 102, with and without S9 mix) and two micronucleus tests with the plant Tradescantia (clone #4430) and with primary rat hepatocytes. Overall, the tested Austrian groundwater samples used for human consumption caused only weak genotoxic activities compared to drinking water samples reported from othercountries under similar experimental conditions. With the exception of oneweak positive result in the Ames test (only in strain TA98 without S9 mix)with an induction factor of 1.9) all samples after UV disinfection were devoid of additional mutagenic and clastogenic activities compared to the samples before UV disinfection. (C) 2001 Elsevier Science Ltd. All rights reserved.

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Documento generato il 10/07/20 alle ore 12:46:08