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Titolo:
Regional brain perfusion in 10 normal dogs measured using technetium-99m ethyl cysteinate dimer SPECT
Autore:
Peremans, K; De Bondt, P; Audenaert, K; Van Laere, K; Gielen, I; Koole, M; Versijpt, J; Van Bree, H; Verschooten, F; Dierckx, R;
Indirizzi:
State Univ Ghent, Fac Vet Med, Dept Med Imaging, B-9820 Merelbeke, BelgiumState Univ Ghent Merelbeke Belgium B-9820 ing, B-9820 Merelbeke, Belgium State Univ Ghent, Div Nucl Med, B-9000 Ghent, Belgium State Univ Ghent Ghent Belgium B-9000 iv Nucl Med, B-9000 Ghent, Belgium State Univ Ghent, Inst Nucl Sci, B-9000 Ghent, Belgium State Univ Ghent Ghent Belgium B-9000 st Nucl Sci, B-9000 Ghent, Belgium
Titolo Testata:
VETERINARY RADIOLOGY & ULTRASOUND
fascicolo: 6, volume: 42, anno: 2001,
pagine: 562 - 568
SICI:
1058-8183(200111/12)42:6<562:RBPI1N>2.0.ZU;2-1
Fonte:
ISI
Lingua:
ENG
Soggetto:
CEREBRAL BLOOD-FLOW; METABOLISM; PATTERN;
Keywords:
dog; scintigraphy; brain perfusion; technetium-99m ethyl cysteinate dimer;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Agriculture,Biology & Environmental Sciences
Citazioni:
29
Recensione:
Indirizzi per estratti:
Indirizzo: Peremans, K State Univ Ghent, Fac Vet Med, Dept Med Imaging, Salisburylaan133, B-9820Merelbeke, Belgium State Univ Ghent Salisburylaan 133 Merelbeke Belgium B-9820 m
Citazione:
K. Peremans et al., "Regional brain perfusion in 10 normal dogs measured using technetium-99m ethyl cysteinate dimer SPECT", VET RAD ULT, 42(6), 2001, pp. 562-568

Abstract

Single photon emission computed tomography (SPECT) of the brain using perfusion tracers allows estimation of regional brain perfusion. This allows invivo examination of brain function in the setting or neuropsychologic and pathophysiologic changes. However functional imaging data on brain perfusion in dogs are limited. Hence, the aim of this study was to determine the scintigraphic regional perfusion pattern of the normal canine brain. Ten healthy shepherd type dogs were injected with 925 MBq Technetium-99m ethyl cysteinate (ECD) 20 minutes before the examination. Acquisition was performed using a triple head gamma camera equipped with fanbeam collimators. Uniform attenuation correction and triple energy window correction were applied. Computed tomographic images were obtained from the same dogs, reoriented along the orbito-meatal axis and SPECT perfusion data were coregistered to the CT-volume data. Based on morphological and suggested brain divisions, regions-of-interest (ROIs) were defined for the bilateral frontocerebral, temporocerebral, parietocerebral, occipitocerebral, cerebellar, thalamic, and striatal area. Regional count density was normalized on total counts. All dogshad the highest uptake in the thalamic/striatal area compared to a rather homogeneous cerebral uptake. No significant left/right count differences were found, but a rostro-caudal gradient (+12-13%) was present. In this group, age and gender did not influence the perfusion pattern.

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Documento generato il 02/04/20 alle ore 19:05:03