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Titolo:
"Stable" inertial cavitation
Autore:
Church, CC; Carstensen, EL;
Indirizzi:
Acusphere Inc, Cambridge, MA 02139 USA Acusphere Inc Cambridge MA USA 02139 usphere Inc, Cambridge, MA 02139 USA Univ Rochester, Rochester, NY USA Univ Rochester Rochester NY USAUniv Rochester, Rochester, NY USA
Titolo Testata:
ULTRASOUND IN MEDICINE AND BIOLOGY
fascicolo: 10, volume: 27, anno: 2001,
pagine: 1435 - 1437
SICI:
0301-5629(200110)27:10<1435:"IC>2.0.ZU;2-Y
Fonte:
ISI
Lingua:
ENG
Soggetto:
SONOLUMINESCENCE; MICROBUBBLES; DESTRUCTION; ULTRASOUND; DYNAMICS;
Keywords:
cavitation threshold; contrast agent; inertial cavitation; microbubble;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
9
Recensione:
Indirizzi per estratti:
Indirizzo: Church, CC Acusphere Inc, 38 Sidney St, Cambridge, MA 02139 USA Acusphere Inc 38 Sidney St Cambridge MA USA 02139 MA 02139 USA
Citazione:
C.C. Church e E.L. Carstensen, ""Stable" inertial cavitation", ULTRASOUN M, 27(10), 2001, pp. 1435-1437

Abstract

This note compares theoretical predictions of pressure waves scattered by free gas bubbles with recent acoustical determinations of cavitation thresholds for individual microbubbles of the surfactant-stabilized contrast agent Sonazoid (R). The results indicate that surfactant-coated microbubbles undergo "stable" (i.e., repetitive) inertial cavitation above a threshold of 0.3 to 0.4 MPa at 2.5 MHz, and that irreversible postcollapse bubble fragmentation usually requires much higher pressures (similar to1.5 MPa). Adversebioeffects can be expected in vivo far below these fragmentation pressureswhen contrast agents are present. With diagnostically relevant exposures, the threshold for the generation of petechiae in skeletal muscle is similarto0.6 MPa at 2.5 MHz. (C) 2001 World Federation for Ultrasound in Medicine& Biology.

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Documento generato il 31/03/20 alle ore 21:57:17