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Titolo:
Malaria vaccine trials in a wormy world
Autore:
Nacher, M;
Indirizzi:
Mahidol Univ, Fac Trop Med, Bangkok 10400, Thailand Mahidol Univ BangkokThailand 10400 ac Trop Med, Bangkok 10400, Thailand
Titolo Testata:
TRENDS IN PARASITOLOGY
fascicolo: 12, volume: 17, anno: 2001,
pagine: 563 - 565
SICI:
1471-4922(200112)17:12<563:MVTIAW>2.0.ZU;2-Z
Fonte:
ISI
Lingua:
ENG
Soggetto:
PAPUA-NEW-GUINEA; HELMINTH INFECTIONS; FALCIPARUM MALARIA; SPF66 VACCINE; CHILDREN; RESPONSES; IMMUNITY; IMMUNIZATION; PROTECTION; TANZANIA;
Tipo documento:
Editorial Material
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
37
Recensione:
Indirizzi per estratti:
Indirizzo: Nacher, M Mahidol Univ, Fac Trop Med, 420-6 Rajvithi Rd, Bangkok 10400, Thailand Mahidol Univ 420-6 Rajvithi Rd Bangkok Thailand 10400 Thailand
Citazione:
M. Nacher, "Malaria vaccine trials in a wormy world", TRENDS PARA, 17(12), 2001, pp. 563-565

Abstract

The promising malaria vaccine candidates that have been tested in the field have, so far, yielded disappointing and, at times, conflicting results. Considerable efforts are being made to isolate new immunogenic molecules. However, the fact that most populations in malaria endemic areas are also infected by helminths appears to be overlooked. Helminth-related hyporesponsiveness to tetanus or cholera vaccines, and the interactions between malaria parasites and helminths, raise the possibility that a potent malaria vaccine will not be identified in helminth-infected populations, thus necessitating a change in vaccine trial design.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 02/04/20 alle ore 13:05:19