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Titolo:
Origin and differentiation of dendritic cells
Autore:
Ardavin, C; del Hoyo, GM; Martin, P; Anjuere, F; Arias, CF; Marin, AR; Ruiz, S; Parrillas, V; Hernandez, H;
Indirizzi:
Univ Complutense, Fac Biol, Dept Cell Biol, E-28040 Madrid, Spain Univ Complutense Madrid Spain E-28040 t Cell Biol, E-28040 Madrid, Spain Fac Med Pasteur, Lab Immunol Cellulaire & Mol, INSERM U364, F-06107 Nice 2, France Fac Med Pasteur Nice France 2 & Mol, INSERM U364, F-06107 Nice 2, France
Titolo Testata:
TRENDS IN IMMUNOLOGY
fascicolo: 12, volume: 22, anno: 2001,
pagine: 691 - 700
SICI:
1471-4906(200112)22:12<691:OADODC>2.0.ZU;2-#
Fonte:
ISI
Lingua:
ENG
Soggetto:
COLONY-STIMULATING FACTOR; HEMATOPOIETIC PROGENITOR CELLS; NECROSIS-FACTOR-ALPHA; LANGERHANS CELLS; IN-VIVO; HUMAN BLOOD; PRECURSOR CELLS; NATURAL-KILLER; FLT3 LIGAND; TRANSFORMING GROWTH-FACTOR-BETA-1;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
67
Recensione:
Indirizzi per estratti:
Indirizzo: Ardavin, C Univ Complutense, Fac Biol, Dept Cell Biol, E-28040 Madrid, Spain Univ Complutense Madrid Spain E-28040 , E-28040 Madrid, Spain
Citazione:
C. Ardavin et al., "Origin and differentiation of dendritic cells", TRENDS IMMU, 22(12), 2001, pp. 691-700

Abstract

Despite extensive, recent research on the development of dendritic cells (DCs), their origin is a controversial issue in immunology, with important implications regarding their use in cancer immunotherapy. Although, under defined experimental conditions, DCs can be generated from myeloid or lymphoid precursors, the differentiation pathways that generate DCs in vivo remainunknown largely. Indeed, experimental results suggest that the in vivo differentiation of a particular DC subpopulation could be unrelated to its possible experimental generation. Nevertheless, the analysis of DC differentiation by in vivo and in vitro experimental systems could provide important insights into the control of the physiological development of DCs and constitutes the basis of a model of common DC differentiation that we propose.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/01/20 alle ore 09:27:12