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Titolo:
Tissue factor in the heart - Multiple roles in hemostasis, thrombosis, andinflammation
Autore:
Luther, T; Mackman, N;
Indirizzi:
Scripps Res Inst, Res Inst, Dept Immunol, La Jolla, CA 92037 USA Scripps Res Inst La Jolla CA USA 92037 pt Immunol, La Jolla, CA 92037 USA Tech Univ Dresden, Univ Klinikum Carl Gustav Carus, D-8027 Dresden, Germany Tech Univ Dresden Dresden Germany D-8027 Carus, D-8027 Dresden, Germany
Titolo Testata:
TRENDS IN CARDIOVASCULAR MEDICINE
fascicolo: 8, volume: 11, anno: 2001,
pagine: 307 - 312
SICI:
1050-1738(200111)11:8<307:TFITH->2.0.ZU;2-U
Fonte:
ISI
Lingua:
ENG
Soggetto:
VENTRICULAR MYOCARDIUM; FACTOR EXPRESSION; GAP-JUNCTIONS; FACTOR-VIIA; CELL-ADHESION; INFARCT SIZE; LOCALIZATION; LIPOPOLYSACCHARIDE; VASCULOPATHY; REPERFUSION;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
41
Recensione:
Indirizzi per estratti:
Indirizzo: Mackman, N Scripps Res Inst, Res Inst, Dept Immunol, C-204,10550 N Torrey Pines Rd, La Jolla, CA 92037 USA Scripps Res Inst C-204,10550 N Torrey Pines Rd La Jolla CA USA 92037
Citazione:
T. Luther e N. Mackman, "Tissue factor in the heart - Multiple roles in hemostasis, thrombosis, andinflammation", TREND CARD, 11(8), 2001, pp. 307-312

Abstract

Tissue factor (TF) is the primary cellular initiator of the coagulation protease cascade. It plays an essential role in hemostasis to limit hemorrhage in the event of vascular injury. Indeed, loss of TF is incompatible with life. Recent studies have suggested that TF also plays non-hemostatic rolesin blood vessel development, tumor angiogenesis, tumor metastasis, cell migration, and inflammation. This review discusses the roles of TF in hemostasis, thrombosis, and inflammation in the heart as well as other potential roles of TF in the maintenance of cardiac muscle. (C) 2001, Elsevier ScienceInc.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 21/01/20 alle ore 07:46:43