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Titolo:
Campylobacter: the new leader in food-borne disease aetiology
Autore:
Rollins, DM; Joseph, SW;
Indirizzi:
Univ Maryland, Dept Cell Biol & Mol Genet, College Pk, MD 20742 USA Univ Maryland College Pk MD USA 20742 Mol Genet, College Pk, MD 20742 USA
Titolo Testata:
REVIEWS IN MEDICAL MICROBIOLOGY
fascicolo: 4, volume: 12, anno: 2001,
pagine: 187 - 198
SICI:
0954-139X(200110)12:4<187:CTNLIF>2.0.ZU;2-U
Fonte:
ISI
Lingua:
ENG
Soggetto:
ENTERO-TOXIN PRODUCTION; GUILLAIN-BARRE-SYNDROME; HEALTHY LAYING HENS; FETUS SUBSP-JEJUNI; HEP-2 CELLS; INTRACELLULAR SURVIVAL; MOLECULAR MIMICRY; IRON ACQUISITION; HOST STRUCTURES; CYTO-TOXIN;
Keywords:
Campylobacter; food-borne; gastroenteritis; diarrhoea; toxins; epidemiology;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
75
Recensione:
Indirizzi per estratti:
Indirizzo: Joseph, SW Univ Maryland, Dept Cell Biol & Mol Genet, College Pk, MD 20742USA Univ Maryland College Pk MD USA 20742 College Pk, MD 20742 USA
Citazione:
D.M. Rollins e S.W. Joseph, "Campylobacter: the new leader in food-borne disease aetiology", REV MED MIC, 12(4), 2001, pp. 187-198

Abstract

In the genus Campylobacter there are 15 species, three of which are significant human pathogens. The organism is a uniquely small, Gram-negative rod found primarily in zoonotic reservoirs from which humans can be infected. Different clinical features ranging from watery diarrhoea to dysentery and subsequent possible sequelae result from infection. Several immunodominant antigens are now recognized and these have been exploited for use in epidemiological typing methods and are gradually being analyzed to determine theirrole in pathogenesis. Although the nature of Campylobacter pathogenesis remains elusive, some information is now available on adherence, invasion andtoxicity. Fortunately, clinical laboratory diagnosis is now routine and numerous molecular characterization procedures are potentially available. Vaccine development is underway, but thus far, significant protection has not been demonstrated. Fluoroquinolones remain the drugs of choice for severe gastroenteritis, although resistance to these antibiotics and to the macrolides, is beginning to emerge. (C) 2001 Lippincott Williams & Wilkins.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/03/20 alle ore 09:13:18