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Titolo:
Evaluation of the precision of magnetic resonance phase velocity mapping for blood flow measurements
Autore:
Chatzimavroudis, GP; Oshinski, JN; Franch, RH; Walker, PG; Yoganathan, AP; Pettigrew, RI;
Indirizzi:
Cleveland State Univ, Dept Chem Engn, Cleveland, OH 44115 USA Cleveland State Univ Cleveland OH USA 44115 Engn, Cleveland, OH 44115 USA Emory Univ, Sch Med, Dept Radiol, Frederik Philips Magnet Resonance Res Ctr, Atlanta, GA 30322 USA Emory Univ Atlanta GA USA 30322 Resonance Res Ctr, Atlanta, GA 30322 USA Emory Univ, Sch Med, Dept Med, Div Cardiol, Atlanta, GA 30322 USA Emory Univ Atlanta GA USA 30322 t Med, Div Cardiol, Atlanta, GA 30322 USA Univ Leeds, Dept Mech Engn, Leeds LS2 9JT, W Yorkshire, England Univ Leeds Leeds W Yorkshire England LS2 9JT S2 9JT, W Yorkshire, England Georgia Inst Technol, Dept Biomed Engn, Atlanta, GA 30332 USA Georgia InstTechnol Atlanta GA USA 30332 med Engn, Atlanta, GA 30332 USA
Titolo Testata:
JOURNAL OF CARDIOVASCULAR MAGNETIC RESONANCE
fascicolo: 1, volume: 3, anno: 2001,
pagine: 11 - 19
SICI:
1097-6647(2001)3:1<11:EOTPOM>2.0.ZU;2-J
Fonte:
ISI
Lingua:
ENG
Soggetto:
AORTIC REGURGITATION MEASUREMENTS; SLICE LOCATION; MR; QUANTIFICATION; QUANTITATION; ARTERIES; PATTERNS;
Keywords:
accuracy; aortic regurgitation; flow quantification; magnetic resonance; magnetic resonance phase velocity mapping; precision;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
22
Recensione:
Indirizzi per estratti:
Indirizzo: Pettigrew, RI Emory Univ, Sch Med, Dept Radiol, Frederik Philips Magnet Resonance Res Ctr, 1364 Clifton Rd, Atlanta, GA 30322 USA Emory Univ 1364 Clifton Rd Atlanta GA USA 30322 GA 30322 USA
Citazione:
G.P. Chatzimavroudis et al., "Evaluation of the precision of magnetic resonance phase velocity mapping for blood flow measurements", J CARD M RE, 3(1), 2001, pp. 11-19

Abstract

Evaluating the in vivo accuracy of magnetic resonance phase velocity. mapping (PVM) is not straightforward because of the absence of a validated clinical flow quantification technique. The aim of this study was to evaluate PVM by investigating its precision, both in vitro and in vivo, in a 1.5 Tesla scanner In the former case, steady and pulsatile flow experiments were conducted using an aortic model under a variety of flow conditions (steady : 0.1-5.5 L/min, pulsatile. 10-75 mL/cycle). In the latter case, PVM measurements were taken in the ascending aorta often subjects, seven of which hem aortic regurgitation. Each velocity measurement was taken twice, with the slice perpendicular to the long axis of the aorta. Comparison between, the measured and true flow rates and volumes confirmed the high accuracy of PVM in measuring pou in vitro (p > 0.85). The in vitro precision of PVM was found to be very high (steady: y = 1.00x + 0.02. r = 0.999: pulsatile: y = 0.98x + 0.72. r = 0.997: x: measurement #1, y : measurement #2) and this was confirmed by Bland-Airman analysis. Of great clinical significance was the high level of the in vivo precision (y = 1.01x - 0.04. r = 0.993), confirmed statistically (p = 1.00). In conclusion. PVM provides repeatable bloodflow measurements. The high in vitro accuracy and precision, combined with the high in vivo precision, are key factors for the establishment of PVM as the "gold-standard" to quantify bloodflow.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 27/01/20 alle ore 16:54:45