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Titolo:
Exercise induces gastric ischemia in healthy volunteers: a tonometry study
Autore:
Otte, JA; Oostveen, E; Geelkerken, RH; Groeneveld, ABJ; Kolkman, JJ;
Indirizzi:
Med Spectrum Twente, Dept Internal Med & Gastroenterol, Enschede, Netherlands Med Spectrum Twente Enschede Netherlands enterol, Enschede, Netherlands Med Spectrum Twente, Dept Pulmonol, Enschede, Netherlands Med Spectrum Twente Enschede Netherlands ulmonol, Enschede, Netherlands Med Spectrum Twente, Dept Surg, Enschede, Netherlands Med Spectrum TwenteEnschede Netherlands pt Surg, Enschede, Netherlands Free Univ Amsterdam Hosp, Med Intens Care Unit, Amsterdam, Netherlands Free Univ Amsterdam Hosp Amsterdam Netherlands , Amsterdam, Netherlands
Titolo Testata:
JOURNAL OF APPLIED PHYSIOLOGY
fascicolo: 2, volume: 91, anno: 2001,
pagine: 866 - 871
SICI:
8750-7587(200108)91:2<866:EIGIIH>2.0.ZU;2-9
Fonte:
ISI
Lingua:
ENG
Soggetto:
BLOOD-FLOW; CLINICAL-APPLICATIONS; MESENTERIC ARTERIAL; PCO2 MEASUREMENT; IN-VITRO; INTENSITY; METHODOLOGY; ULTRASOUND; PHYSIOLOGY; PERFUSION;
Keywords:
gastric mucosal perfusion; exercise testing; intragastric carbon dioxide pressure;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
44
Recensione:
Indirizzi per estratti:
Indirizzo: Otte, JA Streekziekenhuis Honte, Dept Internal Med, Wielingenlaan 2, NL-4535 PA Terneuzen, Netherlands Streekziekenhuis Honte Wielingenlaan 2 Terneuzen Netherlands NL-4535 PA
Citazione:
J.A. Otte et al., "Exercise induces gastric ischemia in healthy volunteers: a tonometry study", J APP PHYSL, 91(2), 2001, pp. 866-871

Abstract

Heavy physical exercise may cause gastrointestinal signs and symptoms, and, although splanchnic blood flow may decrease through redistribution by more than 50%, it is unclear whether these signs and symptoms relate to gastrointestinal ischemia. In 10 healthy volunteers, we studied the effect of exercise on gastric mucosal perfusion adequacy using air tonometry. Two relatively short (10 min) exercise stages were conducted on a cycle ergometer, aiming for 80 and 100% of maximum heart rate, respectively. The intragastric-arterial PCO2 gradient (Delta PCO2) was elevated by 1.1 +/-1.0 kPa over baseline values (-0.1 +/-0.3 kPa) only after maximal exercise (P < 0.001). <Delta>PCO2 positively correlated with the arterial lactate level taken as an index of exercise intensity (Spearman's rank test: r = 0.76, P < 0.0001). By bilinear regression analysis, a lactate level of 12 mmol/l, above which asharp rise in the <Delta>PCO2 occurred, was calculated. We conclude that, in healthy volunteers with normal splanchnic vasculature, gastric ischemia may develop during maximal exercise as judged from intragastric PCO2 tonometry.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 10/07/20 alle ore 18:45:35