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Titolo:
Reproducibility of two coronary calcium quantification algorithms in patients with different degrees of calcification
Autore:
Mohlenkamp, S; Behrenbeck, TR; Pump, H; Kriener, P; Lange, S; Baumgart, D; Seibel, RMM; Gronemeyer, DHW; Erbel, R;
Indirizzi:
Univ Essen, Dept Cardiol, Essen, Germany Univ Essen Essen GermanyUniv Essen, Dept Cardiol, Essen, Germany Mayo Clin & Mayo Fdn, Div Cardiovasc Dis & Internal Med, Rochester, MN 55905 USA Mayo Clin & Mayo Fdn Rochester MN USA 55905 Med, Rochester, MN 55905 USA Univ Witten Herdecke, Inst Diagnost & Intervent Radiol, Mulheim, Germany Univ Witten Herdecke Mulheim Germany Intervent Radiol, Mulheim, Germany Univ Witten Herdecke, Dept Radiol & MicroTherapy, Bochum, Germany Univ Witten Herdecke Bochum Germany iol & MicroTherapy, Bochum, Germany
Titolo Testata:
INTERNATIONAL JOURNAL OF CARDIAC IMAGING
fascicolo: 2, volume: 17, anno: 2001,
pagine: 133 - 142
SICI:
0167-9899(200104)17:2<133:ROTCCQ>2.0.ZU;2-1
Fonte:
ISI
Lingua:
ENG
Soggetto:
BEAM COMPUTED-TOMOGRAPHY; ARTERY CALCIFICATION; LUMEN STENOSIS; DISEASE; CT; PLAQUE; QUANTITATION; SEVERITY;
Keywords:
coronary calcification; electron beam CT (EBT); follow-up; reproducibility;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
31
Recensione:
Indirizzi per estratti:
Indirizzo: Mohlenkamp, S Univ Clin Essen, Dept Cardiol, Hufelandstr 55, D-45122 Essen, Germany Univ Clin Essen Hufelandstr 55 Essen Germany D-45122 ermany
Citazione:
S. Mohlenkamp et al., "Reproducibility of two coronary calcium quantification algorithms in patients with different degrees of calcification", INT J CAR I, 17(2), 2001, pp. 133-142

Abstract

Purpose: To evaluate the reproducibility of coronary calcium quantification algorithms by electron beam CT (EBT) in patients with different amounts of calcified plaque using the conventional (Agatston) score and an area score and to demonstrate a potential application of these results for evaluation of follow-up scans. Methods: In 50 consecutive patients, the conventionalcalcium score (CCS = Agatston score) and the area score (AS) were summed for each artery and patient. Data were analyzed in four groups according to degrees of calcification: 0 (absent-minimal): CCS 0-9, I (mild): CCS 10-99,II (moderate): CCS 100-399, III (severe): CCS greater than or equal to 400. We determined and compared the reproducibility for each algorithm within and among groups. Results: Median percent reproducibility improved with increasing amounts of calcified plaque for the CCS and the AS (p = 0.002 and p= 0.004, respectively). We demonstrate how these reproducibility values can be used to evaluate long-term follow-up studies. The reduction of median reproducibility per patient using the AS vs. the CCS was 32% (13 vs. 19%, respectively). On a vessel-by-vessel basis, the reduction of median reproducibility was 7% (24.3 vs. 22.6%, CCS vs. AS, p < 0.02), which was attributable to a 45% reduction in reproducibility in arteries with mild scores (46.1vs. 25.5%, CCS vs. AS, p < 0.005). Conclusion: The AS has an improved reproducibility compared with the CCS, especially in patients with small amounts of coronary calcifications which may prove clinically useful. Different reproducibility values in different degrees of calcification can be used foran individual assessment of changes in amounts of coronary calcification.

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Documento generato il 30/03/20 alle ore 00:46:56