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Titolo:
Inflammatory bowel disease and laterality: is left handedness a risk?
Autore:
Morris, DL; Montgomery, SM; Galloway, ML; Pounder, RE; Wakefield, AJ;
Indirizzi:
Royal Free & Univ Coll Hosp, Sch Med, Inflammatory Bowel Dis Study Grp, London NW3 2PF, England Royal Free & Univ Coll Hosp London England NW3 2PF ndon NW3 2PF, England Karolinska Sjukhuset & Inst, Enheten Klin Epidemiol, Stockholm, Sweden Karolinska Sjukhuset & Inst Stockholm Sweden idemiol, Stockholm, Sweden
Titolo Testata:
GUT
fascicolo: 2, volume: 49, anno: 2001,
pagine: 199 - 202
SICI:
0017-5749(200108)49:2<199:IBDALI>2.0.ZU;2-1
Fonte:
ISI
Lingua:
ENG
Soggetto:
BEHAN-GALABURDA MODEL; CEREBRAL LATERALIZATION; HAND PREFERENCE; CROHNS-DISEASE; ASSOCIATION; BIRTH; PREVALENCE; DISORDERS; COHORT;
Keywords:
inflammatory bowel disease; handedness;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
27
Recensione:
Indirizzi per estratti:
Indirizzo: Morris, DL Royal Free & Univ Coll Hosp, Sch Med, Inflammatory Bowel Dis Study Grp, Rowland Hill St, London NW3 2PF, England Royal Free & Univ Coll Hosp Rowland Hill St London England NW3 2PF
Citazione:
D.L. Morris et al., "Inflammatory bowel disease and laterality: is left handedness a risk?", GUT, 49(2), 2001, pp. 199-202

Abstract

Background - Left handedness has been associated with inflammatory bowel disease (IBD) and autoimmune diseases. Aims - determine whether left handedness is associated with IBD in two prospective national birth cohorts. Methods - Subjects with Crohn's disease (CD) and ulcerative colitis (UC) were identified from two national longitudinal birth cohorts at age 26 years(1970 British Cohort Study (BCS70), born in 1970) and age 33 years (National Child Development Study (NCDS), born in 1958). Laterality was determinedat age 10 (BCS70) or seven (NCDS) years, based on hand preference for writing and foot preference for kicking a ball (BCS70 only). Multiple logistic regression was used to assess the relationship of handedness with CD, UC, and IBD in the cohorts combined and adjusted for sex. Results - Both cohorts combined showed increased adjusted relative odds of2.13 (95% confidence interval (CT) 0.97-4.65; p=0.059), 2.13 (95% CI 0.92-4.91; p=0.077), and 2.13 (95% CI 1.20- 3.78; p=0.010) for CD, UC, and IBD, respectively in left handers. Conclusions - The study suggests a link between IBD and left handedness which may be genetic and/or environmental in origin.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 30/03/20 alle ore 13:22:13