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Titolo:
Micronuclei and other nuclear lesions as genotoxicity indicators in rainbow trout Oncorhynchus mykiss
Autore:
Ayllon, F; Garcia-Vazquez, E;
Indirizzi:
Univ Oviedo, Fac Med, Dept Biol Func, Area Genet, E-33006 Oviedo, Spain Univ Oviedo Oviedo Spain E-33006 Func, Area Genet, E-33006 Oviedo, Spain
Titolo Testata:
ECOTOXICOLOGY AND ENVIRONMENTAL SAFETY
fascicolo: 3, volume: 49, anno: 2001,
pagine: 221 - 225
SICI:
0147-6513(200107)49:3<221:MAONLA>2.0.ZU;2-C
Fonte:
ISI
Lingua:
ENG
Soggetto:
SISTER-CHROMATID EXCHANGES; IN-SITU HYBRIDIZATION; ANGUILLA-ANGUILLA L; ETHYL METHANESULFONATE; EASTERN MUDMINNOW; ACRIDINE-ORANGE; UMBRA-PYGMAEA; MITOMYCIN-C; BROWN TROUT; INDUCTION;
Keywords:
genotoxicity; micronuclei; nuclear abnormalities; Oncorhynchus mykiss;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Agriculture,Biology & Environmental Sciences
Life Sciences
Citazioni:
38
Recensione:
Indirizzi per estratti:
Indirizzo: Ayllon, F Univ Oviedo, Fac Med, Dept Biol Func, Area Genet, C Julian Claveria S-N, E-33006 Oviedo, Spain Univ Oviedo C Julian Claveria S-N Oviedo Spain E-33006 o, Spain
Citazione:
F. Ayllon e E. Garcia-Vazquez, "Micronuclei and other nuclear lesions as genotoxicity indicators in rainbow trout Oncorhynchus mykiss", ECOTOX ENV, 49(3), 2001, pp. 221-225

Abstract

The induction of micronuclei and other nuclear abnormalities in renal erythrocytes of rainbow trout Oncorhynchus mykiss by six genotoxic compounds isevaluated, Colchicine, mitomycin cyclophosphamide, acrylamide, methyl-methanesulfonate, and N-ethyl-N-nitrosourea were intraperitoneally injected in trout. Our results show that cyclophosphamide induces the formation of micronuclei and also the other nuclear abnormalities; N-ethyl-N-nitrosourea, acrylamide, and colchicine induce only micronuclei; mitomycin-C induces only other nuclear abnormalities but not micronuclei, Methyl-methanesulfonate does not induce nuclear abnormalities in rainbow trout at the dose assayed inthis work. The possible genotoxic origin for the different nuclear abnormalities is discussed. (C) 2001 Academic Press.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 08/07/20 alle ore 08:08:09