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Titolo:
Clinical manifestations of myocardial stunning
Autore:
Ambrosio, G; Tritto, I;
Indirizzi:
Univ Perugia, Monteluce Policlin, Div Cardiol, I-06122 Perugia, Italy UnivPerugia Perugia Italy I-06122 , Div Cardiol, I-06122 Perugia, Italy
Titolo Testata:
CORONARY ARTERY DISEASE
fascicolo: 5, volume: 12, anno: 2001,
pagine: 357 - 361
SICI:
0954-6928(200108)12:5<357:CMOMS>2.0.ZU;2-#
Fonte:
ISI
Lingua:
ENG
Soggetto:
LEFT-VENTRICULAR DYSFUNCTION; CORONARY-ARTERY DISEASE; EXERCISE-INDUCED ISCHEMIA; UNSTABLE ANGINA; FUNCTIONAL RECOVERY; REGIONAL FUNCTION; REPEATED EPISODES; BYPASS-SURGERY; CONSCIOUS DOGS; WALL MOTION;
Keywords:
left ventricular contractile dysfunction; myocardial ischemia/reperfusion; myocardial stunning;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
38
Recensione:
Indirizzi per estratti:
Indirizzo: Ambrosio, G Univ Perugia, Monteluce Policlin, Div Cardiol, Via Brunamonti,I-06122 Perugia, Italy Univ Perugia Via Brunamonti Perugia Italy I-06122 ugia, Italy
Citazione:
G. Ambrosio e I. Tritto, "Clinical manifestations of myocardial stunning", CORON ART D, 12(5), 2001, pp. 357-361

Abstract

The phenomenon of myocardial stunning has been observed in all animal species studied. The possible occurrence of myocardial stunning in man has beendemonstrated after either regional ischemia (such as exercise-induced angina, vasospastic or unstable angina) or after global ischemia (i.e., after cardioplegic arrest during cardiac surgery, or cardiac arrest, or heart transplantation). Finally, it may also be observed in patients with acute myocardial infarction, subjected to recanalization therapy, because viable myocardium, salvaged by reperfusion, may remain stunned, with delayed contractile recovery. Occurrence of stunning may aggravate hemodynamic conditions in already unstable patients, and it may lead to underestimation of the extent of myocardium salvaged by thrombolysis. Repeated episodes of stunning may lead to a condition of apparently 'chronic' contractile dysfunction that may be difficult to differentiate from hibernation, because of the technical difficulties in accurately measuring myocardial blood flow in patients, and because both phenomena may coexist and overlap in the same patient. In addition, recent evidence suggests that repeated episodes of stunning may lead to a progressive worsening of the residual contractile dysfunction and to longer recovery times, and it has thus been suggested, and it is much debated, that hibernation might at least in part be the consequence of repetitive episodes of stunning. Coron Artery Dis 12:357-361 (C) 2001 Lippincott Williams & Wilkins.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 28/01/20 alle ore 15:24:53