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Titolo:
Localization of voltage-sensitive L-type calcium channels in the chicken retina
Autore:
Firth, SI; Morgan, IG; Boelen, MK; Morgans, CW;
Indirizzi:
Australian Natl Univ, Res Sch Biol Sci, Visual Sci Grp, Canberra, ACT 2601, Australia Australian Natl Univ Canberra ACT Australia 2601 rra, ACT 2601, Australia Australian Natl Univ, Ctr Visual Sci, Canberra, ACT 2601, Australia Australian Natl Univ Canberra ACT Australia 2601 rra, ACT 2601, Australia La Trobe Univ, Div Biol Sci, Bendigo, Vic, Australia La Trobe Univ Bendigo Vic Australia iv Biol Sci, Bendigo, Vic, Australia Australian Natl Univ, John Curtin Sch Med Res, Div Neurosci, Canberra, ACT2601, Australia Australian Natl Univ Canberra ACT Australia 2601 erra, ACT2601, Australia
Titolo Testata:
CLINICAL AND EXPERIMENTAL OPHTHALMOLOGY
fascicolo: 3, volume: 29, anno: 2001,
pagine: 183 - 187
SICI:
1442-6404(200106)29:3<183:LOVLCC>2.0.ZU;2-8
Fonte:
ISI
Lingua:
ENG
Soggetto:
STATIONARY NIGHT BLINDNESS; GATED CA2+ CHANNELS; BIPOLAR CELLS; CONE PHOTORECEPTORS; ALPHA(1D) SUBUNIT; HORIZONTAL CELLS; GENE-EXPRESSION; MESSENGER-RNA; RAT RETINA; CURRENTS;
Keywords:
alpha 1 subunits; calcium channels; chicken; immunohistochemistry; Muller cells; retina;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
29
Recensione:
Indirizzi per estratti:
Indirizzo: Firth, SI Univ Texas, Dept Neurobiol & Anat, 6431 Fannin St, Houston, TX 77030 USA Univ Texas 6431 Fannin St Houston TX USA 77030 ton, TX 77030 USA
Citazione:
S.I. Firth et al., "Localization of voltage-sensitive L-type calcium channels in the chicken retina", CLIN EXP OP, 29(3), 2001, pp. 183-187

Abstract

L-type calcium channels have been associated with synaptic transmission inthe retina, and are a potential site for modulation of the release of neurotransmitters. The present study documents the immunohistochemical localization of neuronal alpha1 subunits of L-type calcium channels in chicken retina, using antibodies to the alpha 1c, alpha 1d and alpha 1f subunits of L-type calcium channels. The alpha 1c-like subunits were localized to Muller cells, with predominantly radial processes, and a prominent band of horizontal processes in the outer plexiform layer. The antibody to alpha 1d subunits labelled most, if not all, cell bodies. The antibody to a human alpha 1f subunit strongly labelled photoreceptor terminals. Fainter immunoreactivitywas detected in the inner segments of the photoreceptors, a subset of amacrine cells, two bands of labelling in the inner plexiform layer and many ganglion cells. The differential cellular distributions of these alpha1-subunits suggests subtle functional differences in their roles at different cellular locations.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 10/07/20 alle ore 19:13:58