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Titolo:
Introducing economic and quality of life measurements into clinical studies
Autore:
Drummond, M;
Indirizzi:
Univ York, Ctr Hlth Econ, York YO10 5DD, N Yorkshire, England Univ York York N Yorkshire England YO10 5DD O10 5DD, N Yorkshire, England
Titolo Testata:
ANNALS OF MEDICINE
fascicolo: 5, volume: 33, anno: 2001,
pagine: 344 - 349
SICI:
0785-3890(200107)33:5<344:IEAQOL>2.0.ZU;2-D
Fonte:
ISI
Lingua:
ENG
Soggetto:
TRIALS;
Keywords:
cost-effectiveness analysis; quality-adjusted life-years; randomized controlled trials;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
14
Recensione:
Indirizzi per estratti:
Indirizzo: Drummond, M Univ York, Ctr Hlth Econ, York YO10 5DD, N Yorkshire, England Univ York York N Yorkshire England YO10 5DD orkshire, England
Citazione:
M. Drummond, "Introducing economic and quality of life measurements into clinical studies", ANN MED, 33(5), 2001, pp. 344-349

Abstract

Although the collection of cost and quality of life data alongside clinical studies generates detailed patient level data in a timely fashion, it also raises practical and methodological challenges. These include the fact that the settings and patients enrolled in trials may not be typical of thosefound in regular clinical practice, that costs and quality of life may be influenced by the trial protocol, that the clinical alternatives compared in trials may not be the most relevant for cost-effectiveness assessments, that the length of follow-up may be too short to observe changes in cost andquality of life, and that adding these data will increase the overall measurement burden in the trial, This paper discusses these challenges and the ways in which they might be overcome, focussing particularly on preference-based measures of quality of life, In particular, recommendations are givenfor choosing the range of quality of life instruments, sample size calculations for quality of life measurement and the measurement of quality of life in multinational studies.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 20/01/21 alle ore 11:12:29