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Titolo:
The 15D instrument of health-related quality of life: properties and applications
Autore:
Sintonen, H;
Indirizzi:
Univ Helsinki, Dept Publ Hlth, FIN-00014 Helsinki, Finland Univ Helsinki Helsinki Finland FIN-00014 th, FIN-00014 Helsinki, Finland
Titolo Testata:
ANNALS OF MEDICINE
fascicolo: 5, volume: 33, anno: 2001,
pagine: 328 - 336
SICI:
0785-3890(200107)33:5<328:T1IOHQ>2.0.ZU;2-X
Fonte:
ISI
Lingua:
ENG
Soggetto:
OF-LIFE; VALIDITY; RESPONSIVENESS; ADOLESCENCE; PREFERENCES; RELIABILITY; INDEXES; STATES;
Keywords:
15D; cost-effectiveness analysis; cost-utility analysis; economic evaluation; health-related quality of life; health status; QALY; quality of life; sensitivity; utility;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
37
Recensione:
Indirizzi per estratti:
Indirizzo: Sintonen, H Univ Helsinki, Dept Publ Hlth, Box 41, FIN-00014 Helsinki, Finland Univ Helsinki Box 41 Helsinki Finland FIN-00014 inki, Finland
Citazione:
H. Sintonen, "The 15D instrument of health-related quality of life: properties and applications", ANN MED, 33(5), 2001, pp. 328-336

Abstract

The 15D is a generic, comprehensive, 15-dimensional, standardized, self-administered measure of health-related quality of life (HRQoL) that can be used both as a profile and single index score measure. This paper examines the acceptability, reliability, validity, discriminatory power and responsiveness to change of its health state descriptive system and valuation system and presents some examples of applications, As a profile measure on roughlycomparable dimensions the 15D performs equally well as the Nottingham Health Profile (NHP) and SF-20, in some respects even better, and clearly better than EQ-5D, The remaining nine to ten dimensions of the 15D provide a large reserve in terms of discriminatory power and responsiveness to change, The valuation system is based on an application of the multiattribute utility theory. The single index score (15D score) on a 0-1 scale, representing the overall HRQoL, is calculated from the health state descriptive system byusing a set of population-based preference or utility weights, The 15D scores are shown to be highly reliable, sensitive and responsive to change, generalisable at least in Western-type societies, and particularly valid for deriving quality-adjusted life years (QALYs) gained for resource allocationpurposes. The instrument is recommended by the Washington Panel and is available in several languages for clinical economic evaluation and populationstudies.

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Documento generato il 20/01/21 alle ore 12:48:14