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Titolo:
Inappropriate fosphenytoin use in the ED
Autore:
Johnson, J; Wrenn, K;
Indirizzi:
Vanderbilt Univ, Med Ctr, Dept Emergency Med, Nashville, TN 37232 USA Vanderbilt Univ Nashville TN USA 37232 gency Med, Nashville, TN 37232 USA
Titolo Testata:
AMERICAN JOURNAL OF EMERGENCY MEDICINE
fascicolo: 4, volume: 19, anno: 2001,
pagine: 293 - 294
SICI:
0735-6757(200107)19:4<293:IFUITE>2.0.ZU;2-K
Fonte:
ISI
Lingua:
ENG
Soggetto:
PHENYTOIN;
Keywords:
anticonvulsants; fosphenytoin; phenytoin; seizures;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
8
Recensione:
Indirizzi per estratti:
Indirizzo: Wrenn, K Vanderbilt Univ, Med Ctr, Dept Emergency Med, 703 Oxford House, Nashville,TN 37232 USA Vanderbilt Univ 703 Oxford House Nashville TN USA 37232 37232 USA
Citazione:
J. Johnson e K. Wrenn, "Inappropriate fosphenytoin use in the ED", AM J EMER M, 19(4), 2001, pp. 293-294

Abstract

The objective of the study was to evaluate how often intravenous(IV) fosphenytoin is used when oral phenytoin loading is possible, The methods included a retrospective chart review of all patients receiving IV fosphenytoin in the emergency department. We prospectively derived criteria that identifypatients with seizures who could receive oral phosphenytoin loading (awakeon arrival, alert, no emesis, and lack of endotracheal intubation, repeated seizures, or status epilepticus after arrival), The setting of the study was at an urban, university hospital emergency department with an annual census of 55,000 patients. The outcomes included the number of patients receiving IV fosphenytoin who could have received oral phenytoin loading. From February 1997 to June 1999, 55 patients received IV fosphenytoin. Thirty of these patients (55%, 95% confidence interval 41%-68%) were felt to have received fosphenytoin appropriately, The remaining 25 (45%, 95% confidence interval 32% 59%) patients could have been loaded orally with phenytoin, In a single institution, fosphenytoin administration is inappropriate almost half the time. Oral phenytoin loading is less expensive and safe. (Am J Emerg Med 2001;19:293-294. Copyright (C) 2001 by W.B. Saunders Company).

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 09/04/20 alle ore 10:15:40