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Titolo:
Parallel synthesis of oligosaccharide conjugated enediynes onto silyl-linked solid-support
Autore:
Matsuda, A; Doi, T; Tanaka, H; Takahashi, T;
Indirizzi:
Tokyo Inst Technol, Dept Appl Chem, Meguro Ku, Tokyo 1528552, Japan Tokyo Inst Technol Tokyo Japan 1528552 , Meguro Ku, Tokyo 1528552, Japan
Titolo Testata:
SYNLETT
fascicolo: 7, , anno: 2001,
pagine: 1101 - 1104
SICI:
0936-5214(200107):7<1101:PSOOCE>2.0.ZU;2-C
Fonte:
ISI
Lingua:
ENG
Soggetto:
POSSESSING DNA INTERCALATOR; C-1027 CHROMOPHORE; KEDARCIDIN CHROMOPHORE; POLYETHYLENE SUPPORTS; CLEAVING ACTIVITIES; PEPTIDE-SYNTHESIS; SUGAR MOIETIES; ANALOGS; LIBRARY;
Keywords:
solid-phase synthesis; oligosaccharides; coupling; thiols;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Physical, Chemical & Earth Sciences
Citazioni:
18
Recensione:
Indirizzi per estratti:
Indirizzo: Takahashi, T Tokyo Inst Technol, Dept Appl Chem, Meguro Ku, 2-12-1 Ookayama, Tokyo 1528552, Japan Tokyo Inst Technol 2-12-1 Ookayama Tokyo Japan 1528552 Japan
Citazione:
A. Matsuda et al., "Parallel synthesis of oligosaccharide conjugated enediynes onto silyl-linked solid-support", SYNLETT, (7), 2001, pp. 1101-1104

Abstract

A solid-phase synthesis of enediyne molecules containing a sugar moiety isreported, polymer-supported (2-mercaptoethyl)glycosides linked through a trialkylsilane linker were coupled to a bromoacetate on an enediyne by S-alkylation. After simple washing of the polymer, mild acid treatment, and evaporation, the desired oligosaccharide conjugated enediynes were isolated in pure form in parallel fashion.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 12/07/20 alle ore 06:24:41