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Titolo:
Radiographic signs of bone destruction in the arthritic temporomandibular joint with special reference to markers of disease activity. A longitudinalstudy
Autore:
Nordahl, S; Alstergren, P; Eliasson, S; Kopp, S;
Indirizzi:
Karolinska Inst, Odontologiska Inst, Dept Clin Oral Physiol, SE-14104 Huddinge, Sweden Karolinska Inst Huddinge Sweden SE-14104 siol, SE-14104 Huddinge, Sweden Karolinska Inst, Odontologiska Inst, Dept Oral Radiol, SE-14104 Huddinge, Sweden Karolinska Inst Huddinge Sweden SE-14104 diol, SE-14104 Huddinge, Sweden
Titolo Testata:
RHEUMATOLOGY
fascicolo: 6, volume: 40, anno: 2001,
pagine: 691 - 694
SICI:
1462-0324(200106)40:6<691:RSOBDI>2.0.ZU;2-D
Fonte:
ISI
Lingua:
ENG
Soggetto:
STANDARD REFERENCE FILMS; PROSPECTIVE FOLLOW-UP; RHEUMATOID-ARTHRITIS; PROGRESSION; INTERLEUKIN-1-BETA; DAMAGE; HAND;
Keywords:
temporomandibular joint; erosion; radiographic progression; CRP; IL-1 beta;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
15
Recensione:
Indirizzi per estratti:
Indirizzo: Nordahl, S Karolinska Inst, Odontologiska Inst, Dept Clin Oral Physiol, Box 4064, SE-14104 Huddinge, Sweden Karolinska Inst Box 4064 Huddinge SwedenSE-14104 inge, Sweden
Citazione:
S. Nordahl et al., "Radiographic signs of bone destruction in the arthritic temporomandibular joint with special reference to markers of disease activity. A longitudinalstudy", RHEUMATOLOG, 40(6), 2001, pp. 691-694

Abstract

Objective. To investigate the progression of radiographic changes of the temporomandibular joint (TMJ) with reference to plasma levels of interleukin-1 beta (IL-1 beta), C-reactive protein (CRP) and disease duration. Methods. Twenty-one patients with chronic inflammatory joint disease and TMJ involvement were included. Individualized tomography of the TMJ was performed twice with an interval of at least 12 months. Blood samples were analysed for IL-1 beta and CRP. Results. Significant progression of the overall grade of radiographic changes occurred during the observation period, whereas erosions showed great interindividual variability. Progression of TMJ bone loss was correlated to raised levels of CRP and, in patients with a diagnosis of rheumatoid arthritis, or with shorter duration, also to plasma IL-1 beta. Conclusion. Progression of overall grade of radiographic changes in the TMJ occurs in patients with chronic inflammatory joint disease. Raised levelsof serum CRP are associated with progression of TMJ hone loss.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/03/20 alle ore 17:38:54