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Titolo:
Thrombosis in Behcet's disease: a retrospective survey from a single UK centre
Autore:
Ames, PRJ; Steuer, A; Pap, A; Denman, AM;
Indirizzi:
Northwick Pk Hosp, Dept Rheumatol, London, England Northwick Pk Hosp London England Hosp, Dept Rheumatol, London, England London Sch Hyg & Trop Med, Med Stat Unit, London WC1, England London Sch Hyg & Trop Med London England WC1 t Unit, London WC1, England
Titolo Testata:
RHEUMATOLOGY
fascicolo: 6, volume: 40, anno: 2001,
pagine: 652 - 655
SICI:
1462-0324(200106)40:6<652:TIBDAR>2.0.ZU;2-Z
Fonte:
ISI
Lingua:
ENG
Soggetto:
FACTOR-V-LEIDEN; VASCULAR INVOLVEMENT; CLINICAL MANIFESTATIONS; THROMBOPHILIC FACTORS; VENOUS THROMBOSIS; MUTATION; ARABIA; RISK;
Keywords:
Behcet's disease; thrombosis; arthritis; vasculitis; sex differences;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
22
Recensione:
Indirizzi per estratti:
Indirizzo: Ames, PRJ 75 Canterbury House,Royal St, London SE1 7EH, England 75 Canterbury House,Royal St London England SE1 7EH H, England
Citazione:
P.R.J. Ames et al., "Thrombosis in Behcet's disease: a retrospective survey from a single UK centre", RHEUMATOLOG, 40(6), 2001, pp. 652-655

Abstract

Objective. To contribute to knowledge of vascular occlusion in Behcet's disease (BD), prevalence and relative risk for thrombosis were ascertained retrospectively in a cohort of Caucasian patients with the disease. Patients. The study included 73 ED patients (36 males, 37 females, mean age 45 +/- 11 yr) attending the Immunology/Rheumatology Department of Northwick Park Hospital. A group of 146 patients without ED, attending the same department, served as a control group. Results. Thrombosis was more frequent in ED patients than in controls (23/13, 32% ris 7/146, 5%, P < 0.001). This was accounted for by a higher prevalence of venous thrombosis in ED patients (18/73, 25% vs 4/146, 3%, P < 0.001). Gender-adjusted data revealed an Ii-fold risk of developing any thrombosis and a 14-fold risk of developing venous thrombosis in ED. After adjusting for differences in age at first symptoms, male BD patients showed a 6-fold higher risk of vein thrombosis. Males reported more often thrombophlebitis (13/36, 36% vs 0/0, P < 0.001), folliculitis (8/36, 22% vs 1/37, 3%, P < 0.01) and retinal vasculitis (13/36, 36%, vs 4/37, 11%, P = 0.01) than females, in whom arthralgia prevailed (23/37, 62%, vs 12/36, 33%, P = 0.01). Conclusion. m our population, ED confers a 14-fold risk of developing venous thrombosis. The risk is sixfold higher in male ED patients, who fare worse than females with regard to thrombophlebitis, folliculitis and retinal vasculitis.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/04/20 alle ore 06:59:30