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Titolo:
Endoscopic findings of radiation esophagitis in concurrent chemoradiotherapy for intrathoracic malignancies (vol 59, pg 273, 2001)
Autore:
Hirota, S; Tsujino, K; Hishikawa, Y; Watanabe, H; Kono, K; Soejima, T; Obayashi, K; Takada, Y; Kono, M; Abe, M;
Indirizzi:
Hyogo Med Ctr Adults, Dept Radiol, Akashi, Hyogo 6738558, Japan Hyogo Med Ctr Adults Akashi Hyogo Japan 6738558 shi, Hyogo 6738558, Japan
Titolo Testata:
RADIOTHERAPY AND ONCOLOGY
fascicolo: 1, volume: 60, anno: 2001,
pagine: 107 - 107
SICI:
0167-8140(200107)60:1<107:EFOREI>2.0.ZU;2-9
Fonte:
ISI
Lingua:
ENG
Keywords:
concurrent chemoradiotherapy; radiation esophagitis; esophageal endoscopy;
Tipo documento:
Correction, Addition
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Life Sciences
Citazioni:
1
Recensione:
Indirizzi per estratti:
Indirizzo: Hirota, S Hyogo Med Ctr Adults, Dept Radiol, 13-70 Kitaojzcho, Akashi, Hyogo 6738558, Japan Hyogo Med Ctr Adults 13-70 Kitaojzcho Akashi Hyogo Japan 6738558
Citazione:
S. Hirota et al., "Endoscopic findings of radiation esophagitis in concurrent chemoradiotherapy for intrathoracic malignancies (vol 59, pg 273, 2001)", RADIOTH ONC, 60(1), 2001, pp. 107-107

Abstract

Background and purpose: The incidence and extent of radiation esophagitis were assessed endoscopically in patients treated with concurrent chemoradiotherapy,Patients and methods: Eighty-two patients who received thoracic radiotherapy for lung, thymic, or esophageal cancer were investigated endoscopically from July 1991 to the end of 1997. Among them, 23 esophageal cancer patients were treated with radiation alone, and the other were treated with concurrent chemoradiotherapy. Esophageal endoscopy was performed during or just after radiotherapy. The presence of radiation esophagitis was assessed and assigned an endoscopic score (i.e. grade 0 for normal, 1 for erythema, 2 forerosion or sloughing, 3 for ulcer, hemorrhage, or stricture). The symptomatic grade was assessed using the RTOG (Radiation Therapy Oncology Group) acute radiation morbidity score. Results: A correlation was seen between endoscopic and RTOG scores. However, even some patients with RTOG grade 0 to 1 had endoscopic grade 3 esophagitis, Endoscopic grade 3 was observed in 16 (27.1%) patients in the concurrent chemoradiotherapy group, whereas it did not occur in any patient in theradiation alone group (P = 0.004). Conclusions: Our results suggest that (1) RTOG score correlates closely toesophageal mucosal damage, and (2) more severe esophagitis occurs in thoseundergoing concurrent chemoradiotherapy than those undergoing radiotherapyalone. (C) 2001 Elsevier Science Ireland Ltd. All rights reserved.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 03/07/20 alle ore 01:12:18