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Titolo:
Hypnotic action of melatonin during daytime administration and its comparison with triazolam
Autore:
Satomura, T; Sakamoto, T; Shirakawa, S; Tsutsumi, Y; Mukai, M; Ohyama, T; Uchimura, N; Maeda, H;
Indirizzi:
Kurume Univ, Dept Neuropsychiat, Sch Med, Fukuoka 8300011, Japan Kurume Univ Fukuoka Japan 8300011 chiat, Sch Med, Fukuoka 8300011, Japan
Titolo Testata:
PSYCHIATRY AND CLINICAL NEUROSCIENCES
fascicolo: 3, volume: 55, anno: 2001,
pagine: 303 - 304
SICI:
1323-1316(200106)55:3<303:HAOMDD>2.0.ZU;2-A
Fonte:
ISI
Lingua:
ENG
Keywords:
hypnotic action; hypothermic action; melatonin; polysomnography; rectal temperature; triazolam;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
3
Recensione:
Indirizzi per estratti:
Indirizzo: Satomura, T Kurume Univ, Dept Neuropsychiat, Sch Med, Kurume 67, Fukuoka 8300011, Japan Kurume Univ Kurume 67 Fukuoka Japan 8300011 ka 8300011, Japan
Citazione:
T. Satomura et al., "Hypnotic action of melatonin during daytime administration and its comparison with triazolam", PSY CLIN N, 55(3), 2001, pp. 303-304

Abstract

The present study was conducted to assess hypnotic action, effects on rectal temperature and dose dependency by daytime administration of exogenous melatonin (MLT) at 1 mg, 3 mg or 6 mg to subjects consisting of seven healthy juvenile adults. As a result, exogenous MLT significantly increased totalsleep time and sleep efficiency, and MLT 6mg was observed to demonstrate hypnotic effects that were nearly equal to those of triazolam at 0.125 mg. Rectal temperature was significantly decreased at MLT 1mg and 3 mg. there were no significant differences observed in the hypothermic effects at MLT 6mg. These results indicate that exogenous MLT had dose-dependent hypnotic action on daytime sleep, and it is possible to consider that this hypnotic action was based on a direct-acting mechanism.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 03/04/20 alle ore 03:36:17