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Titolo:
Necessity of carnitine supplementation in semistarved rats fed a high-fat diet
Autore:
Feng, Y; Guo, CJ; Wei, JY; Yang, JJ; Ge, YZ; Gao, LX;
Indirizzi:
Inst Hyg & Environm Med, Dept Nutr, Tianjin 300050, Peoples R China Inst Hyg & Environm Med Tianjin Peoples R China 300050 , Peoples R China
Titolo Testata:
NUTRITION
fascicolo: 7-8, volume: 17, anno: 2001,
pagine: 628 - 631
SICI:
0899-9007(200107/08)17:7-8<628:NOCSIS>2.0.ZU;2-S
Fonte:
ISI
Lingua:
ENG
Soggetto:
COA CARBOXYLASE GENE; METABOLISM; HYPERTRIGLYCERIDEMIA; ACIDS;
Keywords:
carnitine; lipid; metabolism; semistarvation;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
24
Recensione:
Indirizzi per estratti:
Indirizzo: Guo, CJ Inst Hyg & Environm Med, Dept Nutr, Tianjin 300050, Peoples R China Inst Hyg & Environm Med Tianjin Peoples R China 300050 s R China
Citazione:
Y. Feng et al., "Necessity of carnitine supplementation in semistarved rats fed a high-fat diet", NUTRITION, 17(7-8), 2001, pp. 628-631

Abstract

investigated the effects of carnitine supplementation on lipid metabolism in semistarved rats. The semistarved rats were fed a high-fat diet and halfthe normal energy intake for 2 wk. Carnitine was supplied daily at a dose of 250 mg/kg of body weight. The results showed that the concentration of plasma free carnitine increased significantly in semistarved and carnitine-supplemented rats compared with normal and semistarved rats. The activities of muscle carnitine palmitoyltransferase I and preheparin plasma lipoprotein lipase also were significantly increased in semistarved and carnitine-supplemented rats. The plasma triacylglycerol secretion rate was restored to normal by carnitine supplementation in semistarved rats. Urinary excretion of ketone bodies was reduced significantly after camitine supplementation. We concluded that supplementation of camitine can significantly increase theconcentration of plasma free camitine and improve lipid metabolism in semistarved rats fed a high-fat diet. (C) Elsevier Science Inc. 2001.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 20/01/20 alle ore 10:25:40