Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Imaging of the dopaminergic system in parkinsonism with SPET
Autore:
Tatsch, K;
Indirizzi:
Univ Munich, Klinikum Grosshadern, Dept Nucl Med, D-81377 Munich, Germany Univ Munich Munich Germany D-81377 ept Nucl Med, D-81377 Munich, Germany
Titolo Testata:
NUCLEAR MEDICINE COMMUNICATIONS
fascicolo: 7, volume: 22, anno: 2001,
pagine: 819 - 827
SICI:
0143-3636(200107)22:7<819:IOTDSI>2.0.ZU;2-E
Fonte:
ISI
Lingua:
ENG
Soggetto:
I-123 BETA-CIT; EMISSION COMPUTED-TOMOGRAPHY; DOPA-RESPONSIVE DYSTONIA; TRANSPORTER BINDING; HIGH-AFFINITY; IBZM-SPECT; IODINE-123-BETA-CIT SPECT; DIFFERENTIAL-DIAGNOSIS; SUPRANUCLEAR PALSY; ESSENTIAL TREMOR;
Keywords:
parkinsonism; dopamine transporter; dopamine D2-like receptors; single photon emission tomography;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
81
Recensione:
Indirizzi per estratti:
Indirizzo: Tatsch, K Univ Munich, Klinikum Grosshadern, Dept Nucl Med, Marchioninistr15, D-81377 Munich, Germany Univ Munich Marchioninistr 15 Munich Germany D-81377 h, Germany
Citazione:
K. Tatsch, "Imaging of the dopaminergic system in parkinsonism with SPET", NUCL MED C, 22(7), 2001, pp. 819-827

Abstract

Parkinsonism is a feature of various neurodegenerative diseases. Since it is well known that the dopaminergic system plays a major role in parkinsonism, numerous reports have focused on the assessment of the dopaminergic system in vivo. While the use of positron emission tomography (PET) for routine application is still hampered by its limited availability, single photon emission tomography (SPET) has been shown to deliver comparable results to PET in clinical settings. In recent years SPET investigations of the dopamine transporter and of the dopamine D2-like receptors have provided valuableinformation about the pre- and postsynaptic dopaminergic system in parkinsonism. This article briefly reviews the literature dealing with SPET imaging in parkinsonism and specifically addresses the ligands used, the methodology applied, and the current major clinical applications. ((C) 2001 Lippincott Williams & Wilkins).

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/01/20 alle ore 03:59:22