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Titolo:
Abnormal brain white matter in schizophrenia: a diffusion tensor imaging study
Autore:
Agartz, I; Andersson, JLR; Skare, S;
Indirizzi:
Karolinska Inst, Dept Clin Neurosci, Psychiat Sect, SE-17176 Stockholm, Sweden Karolinska Inst Stockholm Sweden SE-17176 ct, SE-17176 Stockholm, Sweden Karolinska Inst, MR Ctr, SE-17176 Stockholm, Sweden Karolinska Inst Stockholm Sweden SE-17176 tr, SE-17176 Stockholm, Sweden
Titolo Testata:
NEUROREPORT
fascicolo: 10, volume: 12, anno: 2001,
pagine: 2251 - 2254
SICI:
0959-4965(20010720)12:10<2251:ABWMIS>2.0.ZU;2-T
Fonte:
ISI
Lingua:
ENG
Soggetto:
MORPHOMETRY; SYSTEMS;
Keywords:
anisotropy; corpus callosum; diffusion tensor imaging; magnetic resonance imaging; occipital lobes; schizophrenia; white matter;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
25
Recensione:
Indirizzi per estratti:
Indirizzo: Agartz, I Karolinska Inst, Dept Clin Neurosci, Psychiat Sect, SE-17176 Stockholm, Sweden Karolinska Inst Stockholm Sweden SE-17176 76 Stockholm, Sweden
Citazione:
I. Agartz et al., "Abnormal brain white matter in schizophrenia: a diffusion tensor imaging study", NEUROREPORT, 12(10), 2001, pp. 2251-2254

Abstract

Fractional anisotropy and the mean diffusion coefficient were measured in the cerebral volume in 20 schizophrenic and 24 healthy subjects, men and women, using diffusion tensor imaging. In addition, 3D SPGR was used for segmentation of brain tissue into grey and white matter and cerebrospinal fluid. In schizophrenic patients, fractional anisotropy was reduced in the splenium of the corpus callosum and in adjacent occipital white matter. The segmentation revealed no tissue deficits in the volume of reduced fractional anisotropy. The mean diffusion was increased in the total white and grey matter volume of the schizophrenic patients compared with the healthy subjects. The findings support the view that global and regional white matter abnormalities occur in chronic schizophrenia. NeuroReport 12:2251-2254 (C) 2001 Lippincott Williams & Wilkins.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 31/03/20 alle ore 10:35:05