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Titolo:
Orexin (hypocretin) gene expression in rat ependymal cells
Autore:
Kummer, M; Neidert, SJ; Johren, O; Dominiak, P;
Indirizzi:
Univ Clin Lubeck, Inst Expt & Clin Pharmacol & Toxicol, D-23538 Lubeck, Germany Univ Clin Lubeck Lubeck Germany D-23538 Toxicol, D-23538 Lubeck, Germany
Titolo Testata:
NEUROREPORT
fascicolo: 10, volume: 12, anno: 2001,
pagine: 2117 - 2120
SICI:
0959-4965(20010720)12:10<2117:O(GEIR>2.0.ZU;2-R
Fonte:
ISI
Lingua:
ENG
Soggetto:
RECEPTOR MESSENGER-RNA; HYPOTHALAMIC NEUROPEPTIDES; LUTEINIZING-HORMONE; HUMAN NARCOLEPSY; SPINAL-CORD; BRAIN; NEURONS; PEPTIDES; IMMUNOREACTIVITY; SECRETION;
Keywords:
brain ventricle; choroid plexus; ependyma; in situ hybridization; prepro-orexin;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
24
Recensione:
Indirizzi per estratti:
Indirizzo: Johren, O Univ Clin Lubeck, Inst Expt & Clin Pharmacol & Toxicol, Ratzeburger Allee 160, D-23538 Lubeck, Germany Univ Clin Lubeck Ratzeburger Allee 160 Lubeck Germany D-23538 y
Citazione:
M. Kummer et al., "Orexin (hypocretin) gene expression in rat ependymal cells", NEUROREPORT, 12(10), 2001, pp. 2117-2120

Abstract

The expression of prepro-orexin (PPO) mRNA in the rat brain was investigated by in situ hybridization histochemistry. In the lateral and posterior hypothalamic areas, which are considered to produce exclusively PPO mRNA, we found high levels of PPO mRNA expressions. We also localized PPO mRNA hybridization signals at lower levels around the lateral ventricles, the third and fourth ventricle. Cellular analysis by emulsion autoradiography revealedthe expression of PPO mRNA in the ependymal cell layer. Our results demonstrate that beside the lateral and posterior hypothalamus PPO mRNA is expressed in ependymal cells. NeuroReport 12:2117-2120 (C) 2001 Lippincott Williams & Wilkins.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 22/01/20 alle ore 12:30:05