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Titolo:
The parkin gene is not a major susceptibility locus for typical late-onsetParkinson's disease
Autore:
Oliveri, RL; Zappia, M; Annesi, G; Annesi, F; Spadafora, P; Pasqua, AA; Tomaino, C; Nicoletti, G; Bosco, D; Messina, D; Logroscino, G; Manobianca, G; Epifanio, A; Morgante, L; Savettieri, G; Quattrone, A;
Indirizzi:
Univ Catanzaro, Neurol Clin, I-88100 Catanzaro, Italy Univ Catanzaro Catanzaro Italy I-88100 ol Clin, I-88100 Catanzaro, Italy CNR, Inst Expt Med & Biotechnol, Piano Lago Di mangone, CS, Italy CNR Piano Lago Di mangone CS Italy nol, Piano Lago Di mangone, CS, Italy Osped Miulli, Acquaviva Fonti, BA, Italy Osped Miulli Acquaviva Fonti BA Italy Miulli, Acquaviva Fonti, BA, Italy Univ Messina, Neurol Clin, Messina, Italy Univ Messina Messina ItalyUniv Messina, Neurol Clin, Messina, Italy Univ Palermo, Neurol Clin, Palermo, Italy Univ Palermo Palermo ItalyUniv Palermo, Neurol Clin, Palermo, Italy
Titolo Testata:
NEUROLOGICAL SCIENCES
fascicolo: 1, volume: 22, anno: 2001,
pagine: 73 - 74
SICI:
1590-1874(200102)22:1<73:TPGINA>2.0.ZU;2-9
Fonte:
ISI
Lingua:
ENG
Soggetto:
RECESSIVE JUVENILE PARKINSONISM; MUTATIONS;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
7
Recensione:
Indirizzi per estratti:
Indirizzo: Zappia, M Univ Catanzaro, Neurol Clin, Via Campanella, I-88100 Catanzaro, Italy Univ Catanzaro Via Campanella Catanzaro Italy I-88100 ro, Italy
Citazione:
R.L. Oliveri et al., "The parkin gene is not a major susceptibility locus for typical late-onsetParkinson's disease", NEUROL SCI, 22(1), 2001, pp. 73-74

Abstract

We investigated the parkin gene in 118 patients with typical Parkinson's disease (PD), i.e. in patients who had an onset of PD after the age of 45 years. The study group included 95 subjects with sporadic PD and 23 subjects from 18 families with autosomal recessive PD. No pathogenetic mutations in the parkin gene were detected either in familial or in sporadic patients. Our findings indicate that the parkin gene is not involved in the pathogenesis of classic late-onset PD.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 20/06/19 alle ore 17:00:40