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Titolo:
Factors influencing survival of diabetic patients after initiation of renal replacement therapy
Autore:
Stoves, J; Baczkowski, AJ; Turney, JH;
Indirizzi:
Leeds Gen Infirm, Dept Nephrol, Leeds, W Yorkshire, England Leeds Gen Infirm Leeds W Yorkshire England , Leeds, W Yorkshire, England Univ Leeds, Dept Stat, Leeds LS2 9JT, W Yorkshire, England Univ Leeds Leeds W Yorkshire England LS2 9JT S2 9JT, W Yorkshire, England
Titolo Testata:
NEPHROLOGY
fascicolo: 2, volume: 6, anno: 2001,
pagine: 79 - 84
SICI:
1320-5358(200104)6:2<79:FISODP>2.0.ZU;2-D
Fonte:
ISI
Lingua:
ENG
Soggetto:
PERITONEAL-DIALYSIS; RISK-FACTORS; HEMODIALYSIS; MORTALITY; COMPLICATIONS; HYPERTENSION; REGRESSION; PREDICTORS; CAPTOPRIL; MELLITUS;
Keywords:
angiotensin-converting; enzyme inhibitors; diabetic renal disease; dialysis; survival analysis; vascular disease;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
30
Recensione:
Indirizzi per estratti:
Indirizzo: Stoves, J St James Univ Hosp, Dept Renal Med, Beckett St, Leeds LS9 7TF, WYorkshire, England St James Univ Hosp Beckett St Leeds W Yorkshire EnglandLS9 7TF
Citazione:
J. Stoves et al., "Factors influencing survival of diabetic patients after initiation of renal replacement therapy", NEPHROLOGY, 6(2), 2001, pp. 79-84

Abstract

The survival of diabetic patients on dialysis treatment is poor but variable. The aim of this retrospective study was to determine factors that mightpredict the survival of such patients in our own unit. Data from 96 patients with diabetic renal disease (biopsy proven or clinically suspected), whohad commenced dialysis after 1980, were included in a retrospective survival analysis. Age, gender, ethnicity, diabetes type, co-morbidity and factors relevant to dialysis provision and subsequent management were considered. The analysis involved the fitting of suitable Cox proportional hazards models using the S-plus statistical software package. According to our model, continued use of angiotensin-converting enzyme (ACE) inhibitor medication and renal replacement with peritoneal dialysis (PD) conferred a survival advantage. In addition, analysis of survival curves showed a significantly better outcome for insulin-dependent diabetic patients, patients on PD and those treated with ACE inhibitor medication. PD may have been associated with improved survival because of its preferential use in younger and fitter diabetic patients (mean age of PD patients at initiation of dialysis 50.3 years compared with 61.6 years for haemodialysis patients). Treatment with ACE inhibitor medication appears to be beneficial and should therefore be considered in all cases.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 27/09/20 alle ore 07:05:38