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Titolo:
Translational control by CPEB: A means to the end
Autore:
Mendez, R; Richter, JD;
Indirizzi:
Univ Massachusetts, Sch Med, Dept Mol Genet & Microbiol, Worcester, MA 01655 USA Univ Massachusetts Worcester MA USA 01655 robiol, Worcester, MA 01655 USA
Titolo Testata:
NATURE REVIEWS MOLECULAR CELL BIOLOGY
fascicolo: 7, volume: 2, anno: 2001,
pagine: 521 - 529
SICI:
1471-0072(200107)2:7<521:TCBCAM>2.0.ZU;2-O
Fonte:
ISI
Lingua:
ENG
Soggetto:
XENOPUS OOCYTE MATURATION; LOCAL PROTEIN-SYNTHESIS; MOS MESSENGER-RNA; CYTOPLASMIC POLYADENYLATION ELEMENTS; INITIATION-FACTOR 4G; C-MOS; BINDING-PROTEIN; POLY(A) POLYMERASE; CYCLIN B1; POLY(A)-BINDING PROTEIN;
Tipo documento:
Review
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
93
Recensione:
Indirizzi per estratti:
Indirizzo: Richter, JD Univ Massachusetts, Sch Med, Dept Mol Genet & Microbiol, Worcester, MA 01655 USA Univ Massachusetts Worcester MA USA 01655 ester, MA 01655 USA
Citazione:
R. Mendez e J.D. Richter, "Translational control by CPEB: A means to the end", NAT REV MOL, 2(7), 2001, pp. 521-529

Abstract

The regulated translation of messenger RNA is essential for cell-cycle progression, establishment of the body plan during early development, and modulation of key activities in the central nervous system. Cytoplasmic polyadenylation, which is one mechanism of controlling translation, is driven by CPEB - a highly conserved, sequence-specific RNA-binding protein that binds to the cytoplasmic polyadenylation element, and modulates translational repression and mRNA localization. What are the features and functions of this multifaceted protein?

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 29/03/20 alle ore 10:27:57