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Titolo:
Risk factors for nosocomial sepsis: a case-control study
Autore:
Alvarez, CF; Farinas, MC; Llorca, J; Rodriguez, MD;
Indirizzi:
Univ Cantabria, Catedra Med Prevent & Salud Publ, Fac Med, Santander 39011, Spain Univ Cantabria Santander Spain 39011 bl, Fac Med, Santander 39011, Spain Hosp Univ Marques Valdecilla, Unidad Enfermedades Infecciosas, Santander, Spain Hosp Univ Marques Valdecilla Santander Spain ecciosas, Santander, Spain Univ Jaen, Dept Ciencias Salud, Jaen, Spain Univ Jaen Jaen SpainUniv Jaen, Dept Ciencias Salud, Jaen, Spain
Titolo Testata:
MEDICINA CLINICA
fascicolo: 20, volume: 116, anno: 2001,
pagine: 765 - 769
SICI:
0025-7753(20010602)116:20<765:RFFNSA>2.0.ZU;2-W
Fonte:
ISI
Lingua:
SPA
Soggetto:
INFLAMMATORY RESPONSE SYNDROME; INTENSIVE-CARE-UNIT; SEPTIC SHOCK; SURGICAL PATIENTS; CDC DEFINITIONS; INFECTION; BACTEREMIA; SURVEILLANCE; PNEUMONIA; SURGERY;
Keywords:
sepsis syndrome; risk factors; cross infection; case-control studies; epidemiology;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
34
Recensione:
Indirizzi per estratti:
Indirizzo: Alvarez, CF Univ Cantabria, Catedra Med Prevent & Salud Publ, Fac Med, Avda Cardenal Herrera Oria S-N, Santander 39011, Spain Univ Cantabria Avda Cardenal Herrera Oria S-N Santander Spain 39011
Citazione:
C.F. Alvarez et al., "Risk factors for nosocomial sepsis: a case-control study", MED CLIN, 116(20), 2001, pp. 765-769

Abstract

Background: The objective of this study was to identify the risk factors associated with the nosocomial sepsis syndrome according to the criteria of the American College of Chest Physicians/Society of Critical Care Medicine Consensus Conference. Patients and Method: A 1-year prospective case-control study matched for sex, age (+/- 5 years), and pre-infection hospital stay (+/- 1 day) was performed in a 1,200-bed university hospital. Cases were selected according to the above criteria. Controls were randomly selected from the daily list of hospitalized patients. Crude and adjusted odds ratios (OR) were determined. Results: 346 cases and 346 controls were included. Multivariate analysis identified the following intrinsic risk factors: coma in the 48 hours beforesepsis (OR: 15.1; CI 95%, 5.6-41.2), renal failure (OR: 3.4; CI 95%; 1.5-10.8), neoplasm (OR: 2.4; CI 95%, 1.1-5.1), prosthesis material (OR: 2.7; CI95%, 1.0-7.8), and serum albumin concentration at admission lower than 3.1g/dl (OR: 5.3; CI 95%, 2.3-12.4). Main extrinsic risk factors were: previous nosocomial infection (OR: 12.5; CI 95%, 1.61-96.3), intensive care unit (ICU) stay (OR: 10.6; CI 95%, 3.1-36.2), naso-gastric tube (OR: 8.4; CI 95%, 2.3-31.3), indwelling urinary catheter (OR: 5.0; CI 95%, 1.4-18.9), H-2 blockers treatment (OR: 5.0; CI 95%, 1.6-15.2), and IV central line (OR: 4.1; CI 95%, 1.2-14.0). Conclusion: In our study, main risk factors for development of nosocomial sepsis were presence of coma in the 48 hours before sepsis, ICU stay, and prior cross infection during hospitalization.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 09/07/20 alle ore 20:44:57