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Titolo:
Effect of compliant intermediate airways on total respiratory resistance and elastance in mechanical ventilation
Autore:
Barbini, P; Cevenini, G; Bernardi, F; Massai, MR; Gnudi, G; Avanzolini, G;
Indirizzi:
Univ Siena, Ist Chirurg Torac & Cardiovasc & Tecnol Biomed, I-53100 Siena,Italy Univ Siena Siena Italy I-53100 vasc & Tecnol Biomed, I-53100 Siena,Italy Univ Bologna, Dipartimento Elettron Informat & Sistemist, I-40136 Bologna,Italy Univ Bologna Bologna Italy I-40136 at & Sistemist, I-40136 Bologna,Italy
Titolo Testata:
MEDICAL ENGINEERING & PHYSICS
fascicolo: 3, volume: 23, anno: 2001,
pagine: 185 - 194
SICI:
1350-4533(200104)23:3<185:EOCIAO>2.0.ZU;2-O
Fonte:
ISI
Lingua:
ENG
Soggetto:
CHEST-WALL IMPEDANCES; NORMAL RANGE; MODEL; SYSTEM; LUNG; FREQUENCY; FAILURE; DOG;
Keywords:
total respiratory resistance and elastance mechanical ventilation; inspiration and expiration; airway viscoelastic properties; breathing mechanics model;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
30
Recensione:
Indirizzi per estratti:
Indirizzo: Barbini, P Univ Siena, Ist Chirurg Torac & Cardiovasc & Tecnol Biomed, ViaLaterina 8, I-53100 Siena, Italy Univ Siena Via Laterina 8 Siena Italy I-53100 100 Siena, Italy
Citazione:
P. Barbini et al., "Effect of compliant intermediate airways on total respiratory resistance and elastance in mechanical ventilation", MED ENG PHY, 23(3), 2001, pp. 185-194

Abstract

Total respiratory resistance and elastance were estimated off-line in a sample of 60 patients undergoing mechanical ventilation by means of two regression models in order to analyse and understand a possible physiological mechanism determining differences in inspiration and expiration. The first model considered a single value for resistance and elastance over a whole breathing cycle, whereas the second model considered separate values for inspiratory and expiratory resistance and a single value for elastance. Inspiratory resistance was found to be lower than expiratory resistance, and intermediate values were obtained for resistance estimated over the whole breathing cycle. Students t-test showed a highly significant difference between these resistance estimates, and principal components analysis demonstrated a significant increase in information when both inspiratory and expiratory resistances were used. Minor differences were found between values of elastance calculated with the two approaches. In an attempt to interpret these experimental results, a lung model incorporating the non-linear viscoelastic properties of the intermediate airways was considered. This model suggested that changes in intermediate airway volume play a significant role in breathing mechanics during artificial ventilation and indicated that inspiratoryand expiratory resistance could be useful parameters for locating airway obstruction. (C) 2001 IPEM. Published by Elsevier Science Ltd. All rights reserved.

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Documento generato il 04/04/20 alle ore 14:17:09