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Titolo:
Hormonal and barrier methods of contraception, oncogenic human papillomaviruses, and cervical squamous intraepithelial lesion development
Autore:
Coker, AL; Sanders, LC; Bond, SM; Gerasimova, T; Pirisi, L;
Indirizzi:
Univ S Carolina, Dept Epidemiol & Biostat, Columbia, SC 29208 USA Univ S Carolina Columbia SC USA 29208 l & Biostat, Columbia, SC 29208 USA S Carolina Dept Hlth & Environm Control, Columbia, SC 29201 USA S CarolinaDept Hlth & Environm Control Columbia SC USA 29201 C 29201 USA Med Univ S Carolina, Coll Nursing, Charleston, SC 29425 USA Med Univ S Carolina Charleston SC USA 29425 ing, Charleston, SC 29425 USA Univ S Carolina, Sch Med, Dept Pathol, Columbia, SC 29208 USA Univ S Carolina Columbia SC USA 29208 Dept Pathol, Columbia, SC 29208 USA
Titolo Testata:
JOURNAL OF WOMENS HEALTH & GENDER-BASED MEDICINE
fascicolo: 5, volume: 10, anno: 2001,
pagine: 441 - 449
SICI:
1524-6094(200106)10:5<441:HABMOC>2.0.ZU;2-D
Fonte:
ISI
Lingua:
ENG
Soggetto:
CARCINOMA IN-SITU; DEPOT-MEDROXYPROGESTERONE ACETATE; ORAL-CONTRACEPTIVES; RISK-FACTORS; INJECTABLE CONTRACEPTIVES; INVASIVE ADENOCARCINOMAS; ADENOSQUAMOUS CARCINOMAS; UTERINE CERVIX; GENITAL-TRACT; YOUNG-WOMEN;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Social & Behavioral Sciences
Clinical Medicine
Citazioni:
51
Recensione:
Indirizzi per estratti:
Indirizzo: Coker, AL Univ S Carolina, Dept Epidemiol & Biostat, Columbia, SC 29208 USA Univ S Carolina Columbia SC USA 29208 t, Columbia, SC 29208 USA
Citazione:
A.L. Coker et al., "Hormonal and barrier methods of contraception, oncogenic human papillomaviruses, and cervical squamous intraepithelial lesion development", J WOMEN H G, 10(5), 2001, pp. 441-449

Abstract

We assessed the influence of hormonal (oral, injectable, or levonorgestrel[Norplant, Wyeth-Ayerst, Philadelphia, PA]) and barrier methods of contraception on the risk of cervical squamous intraepithelial lesions (SIL), while adjusting for high-risk (HR) HPV infection. Subjects were women receivingfamily planning services through the state health department clinics from 1995 to 1998. We selected 60 cases with high-grade cervical/SIL (HSIL) and 316 with low-grade cervical/SIL (LSIL) and controls (427 women with normal cervical cytology) and analyzed cervical DNA for HR-HPV, using Hybrid Capture I (Digene; Gaithersburg, MD). When assessing ever use, duration, recency, latency, and age at first use, neither oral contraceptives (OC), Norplant, nor injectable use was associated with an increased risk of SIL development after adjusting for age, age at first sexual intercourse, and HR-HPV positivity. Among HR-HPV-positive women, longer duration barrier method use was associated with a reduced risk of SIL. This finding has important clinical implications for SIL prevention among HR-HPV-infected women.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/01/20 alle ore 18:56:42