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Titolo:
Renal artery embolization with diluted hot contrast medium: An experimental study
Autore:
Han, YM; Bjarnason, H; Gu, XP; Kong, HF; Urness, M; Gunter, R; Amplatz, K;
Indirizzi:
Chonbuk Natl Univ, Dept Radiol, Sch Med, Chonju 560182, Chonbuk Prov, South Korea Chonbuk Natl Univ Chonju Chonbuk Prov South Korea 560182 rov, South Korea Chonbuk Natl Univ, Inst Cardiovasc Res, Sch Med, Chonju 560182, Chonbuk Prov, South Korea Chonbuk Natl Univ Chonju Chonbuk Prov South Korea 560182 rov, South Korea Univ Minnesota, Fairview Univ Med Ctr, Dept Radiol, Minneapolis, MN 55455 USA Univ Minnesota Minneapolis MN USA 55455 Radiol, Minneapolis, MN 55455 USA Univ Minnesota, Fairview Univ Med Ctr, Dept Lab Med Pathol, Minneapolis, MN 55455 USA Univ Minnesota Minneapolis MN USA 55455 Pathol, Minneapolis, MN 55455 USA
Titolo Testata:
JOURNAL OF VASCULAR AND INTERVENTIONAL RADIOLOGY
fascicolo: 7, volume: 12, anno: 2001,
pagine: 862 - 868
SICI:
1051-0443(200107)12:7<862:RAEWDH>2.0.ZU;2-#
Fonte:
ISI
Lingua:
ENG
Soggetto:
TERM FOLLOW-UP; ETHANOL EMBOLIZATION; ABSOLUTE ETHANOL; ABLATION; NEPHRECTOMY; CARCINOMA; OBLITERATION; COMPONENTS; INJECTION; DISEASE;
Keywords:
arteries, embolization; interventional procedure, experimental; renal arteries, ablation;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
27
Recensione:
Indirizzi per estratti:
Indirizzo: Han, YM Chonbuk Natl Univ, Dept Radiol, Sch Med, Keumam Dong 634-18, Chonju 560182, Chonbuk Prov, South Korea Chonbuk Natl Univ Keumam Dong 634-18 Chonju Chonbuk Prov South Korea 560182
Citazione:
Y.M. Han et al., "Renal artery embolization with diluted hot contrast medium: An experimental study", J VAS INT R, 12(7), 2001, pp. 862-868

Abstract

PURPOSE: To evaluate the safety and efficacy of diluted hot contrast medium to embolize the renal arteries in a canine model. MATERIALS AND METHODS: Transcatheter embolization was performed in 15 dogs(five dogs in each phase: I, II, and control). The diluted hot contrast medium was heated to 90 degreesC-100 degreesC and 30-60 mt were injected intoa renal artery of each dog in phase I (optimization studies) and II (efficacy studies). In the control group, balloon inflation was performed withoutinjection of diluted hot contrast medium. The temperature measurement was performed on one dog in phase I by temperature probe. Follow-up angiographywas performed immediately (n = 15), at 1 week (n = 9), at 1 month (n = 9),and after 3 months (n = 5). All dogs were killed and kidneys were removed for histologic examination. RESULTS: The procedure was performed successfully in all dogs. Follow-up angiography showed complete obstruction of the injected renal arteries in phases I and II. The microscopic findings showed acute full-thickness necrosis of the renal cortex and renal artery in phase I, and complete coagulativenecrosis of the cortex, medulla, and intrarenal blood vessels in phase II. There were no histologic changes of renal veins, inferior vena cava (IVC),and aorta. There were nonspecific findings in the control group. CONCLUSION: This preliminary experimental study suggests that diluted hot contrast medium may be a safe agent for renal ablation without thrombus formation in the renal vein or IVC.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 05/04/20 alle ore 02:39:11