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Titolo:
Genetic and environmental influences on the relationship among combat exposure, posttraumatic stress disorder symptoms, and alcohol use
Autore:
McLeod, DS; Koenen, KC; Meyer, JM; Lyons, MJ; Eisen, S; True, W; Goldberg, J;
Indirizzi:
Columbia Univ, Mailman Sch Publ Hlth, Div Epidemiol, Psychiat Epidemiol Training Program, New York, NY 10032 USA Columbia Univ New York NY USA 10032ining Program, New York, NY 10032 USA Boston Univ, Dept Psychol, Boston, MA 02215 USA Boston Univ Boston MA USA02215 Univ, Dept Psychol, Boston, MA 02215 USA Med Coll Virginia, Dept Human Genet, Richmond, VA USA Med Coll Virginia Richmond VA USA ia, Dept Human Genet, Richmond, VA USA Harvard Inst Psychiat Epidemiol & Genet, Boston, MA USA Harvard Inst Psychiat Epidemiol & Genet Boston MA USA et, Boston, MA USA Harvard Univ, Sch Med, Brockton W Roxbury VA, Dept Psychiat, Brockton, MA USA Harvard Univ Brockton MA USA Roxbury VA, Dept Psychiat, Brockton, MA USA VA Med Ctr, Med Serv, St Louis, MO USA VA Med Ctr St Louis MO USAVA Med Ctr, Med Serv, St Louis, MO USA VA Med Ctr, Res Serv, St Louis, MO USA VA Med Ctr St Louis MO USAVA Med Ctr, Res Serv, St Louis, MO USA Washington Univ, Sch Med, Dept Med, Div Gen Med Sci, St Louis, MO USA Washington Univ St Louis MO USA t Med, Div Gen Med Sci, St Louis, MO USA St Louis Univ, Sch Publ Hlth, St Louis, MO USA St Louis Univ St Louis MO USA ouis Univ, Sch Publ Hlth, St Louis, MO USA Dept Vet Affairs, Hlth Serv Res & Dev, Hines, IL USA Dept Vet Affairs Hines IL USA ffairs, Hlth Serv Res & Dev, Hines, IL USA Univ Illinois, Sch Publ Hlth, Program Epidemiol, Chicago, IL USA Univ Illinois Chicago IL USA bl Hlth, Program Epidemiol, Chicago, IL USA
Titolo Testata:
JOURNAL OF TRAUMATIC STRESS
fascicolo: 2, volume: 14, anno: 2001,
pagine: 259 - 275
SICI:
0894-9867(200104)14:2<259:GAEIOT>2.0.ZU;2-G
Fonte:
ISI
Lingua:
ENG
Soggetto:
TWIN VET REGISTRY; VIETNAM VETERANS; PSYCHIATRIC-DISORDERS; URBAN-POPULATION; YOUNG-ADULTS; WAR; TRAUMA; HERITABILITY; ZYGOSITY; PATTERNS;
Keywords:
posttraumatic stress disorder; alcohol use; combat; genetic; twins;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Social & Behavioral Sciences
Citazioni:
42
Recensione:
Indirizzi per estratti:
Indirizzo: McLeod, DS Columbia Univ, Mailman Sch Publ Hlth, Div Epidemiol, Psychiat Epidemiol Training Program, 630 W 168th St,18th Floor, New York, NY 10032 USA Columbia Univ 630 W 168th St,18th Floor New York NY USA 10032 A
Citazione:
D.S. McLeod et al., "Genetic and environmental influences on the relationship among combat exposure, posttraumatic stress disorder symptoms, and alcohol use", J TRAUMA ST, 14(2), 2001, pp. 259-275

Abstract

The role of generic and environmental influences on the relationship between combat exposure, posttraumatic stress disorder (PTSD) symptoms, and alcohol use were examined in 4072 male-male twin pairs who served in the UnitedStates military during the Vietnam era (1965-1975). Results indicate that the relationship between combat and alcohol use and between PTSD symptom factors and alcohol use were both substantially influenced by genetic factors. Findings are most consistent with a shared vulnerability model for the etiology of the association between PTSD symptoms and alcohol use, Specific unique environmental factors were more important than genetic factors for PTSD symptoms, and both factors were equally important for alcohol use. Further support is also found for the role of the unique environment in PTSD symptoms.

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Documento generato il 25/02/20 alle ore 08:17:49