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Titolo:
Intravenous anesthesia with propofol for painful procedures in children with cancer
Autore:
Jayabose, S; Levendoglu-Tugal, O; Giamelli, J; Grodin, W; Cohn, M; Sandoval, C; Ozkaynak, F; Kubal, K; Nosetti, M; Uman, J; Visintainer, P;
Indirizzi:
New York Med Coll, Sect Pediat Hematol Oncol, Valhalla, NY 10595 USA New York Med Coll Valhalla NY USA 10595 tol Oncol, Valhalla, NY 10595 USA New York Med Coll, Dept Quantitat Hlth Sci, Valhalla, NY 10595 USA New York Med Coll Valhalla NY USA 10595 Hlth Sci, Valhalla, NY 10595 USA Nyack Hosp, Dept Nursing, Nyack, NY USA Nyack Hosp Nyack NY USANyack Hosp, Dept Nursing, Nyack, NY USA Nyack Hosp, Dept Anesthesiol, Nyack, NY USA Nyack Hosp Nyack NY USANyack Hosp, Dept Anesthesiol, Nyack, NY USA Westchester Med Ctr, Dept Anesthesiol, Valhalla, NY USA Westchester Med Ctr Valhalla NY USA , Dept Anesthesiol, Valhalla, NY USA
Titolo Testata:
JOURNAL OF PEDIATRIC HEMATOLOGY ONCOLOGY
fascicolo: 5, volume: 23, anno: 2001,
pagine: 290 - 293
SICI:
1077-4114(200106/07)23:5<290:IAWPFP>2.0.ZU;2-S
Fonte:
ISI
Lingua:
ENG
Soggetto:
PEDIATRIC ONCOLOGY PROCEDURES; THIOPENTONE; SEDATION; MIDAZOLAM; RECOVERY; METHOHEXITONE; INDUCTION; HALOTHANE; FENTANYL; KETAMINE;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
21
Recensione:
Indirizzi per estratti:
Indirizzo: Jayabose, S New York Med Coll, Dept Pediat, Hematol Oncol Sect, Munger Pavil Room 110,Valhalla, NY 10595 USA New York Med Coll Munger Pavil Room 110 Valhalla NY USA 10595
Citazione:
S. Jayabose et al., "Intravenous anesthesia with propofol for painful procedures in children with cancer", J PED H ONC, 23(5), 2001, pp. 290-293

Abstract

Objective: To study the safety and efficacy of propofol-based intravenous anesthesia in children with cancer undergoing painful procedures. Methods: This study is a retrospective analysis of data collected from 52 consecutive children who underwent 335 procedures using propofol anesthesia. These data were routinely collected in all patients: time to induction, duration of the procedure, time to recover, and the doses of the drugs used. Monitoring with electrocardiography and pulse oximetry was continuous during the procedure; blood pressures were recorded before and after the procedure and every 5 to 10 minutes during the procedure. The patients received one of these four propofol-based intravenous regimens according to the anesthesiologist's preference: propofol only; propofol plus fentanyl; propofol plus midazolam; or propofol, fentanyl, and midazolam. The efficacy of sedation was rated by this scoring system: 3 = no movement during procedure; 2 = minimal movement that did not interfere with the procedure; 1 = moderate movement requiring physical restraint to complete the procedure. Results: There were six episodes of mild hypoxia (oxygen saturation 85%-94%) and one episode of laryngospasm. None required intubation. Two patients had agitation and one patient had emesis during the postrecovery phase. There was no difference in the efficacy of sedation between the four regimens. Patients receiving the combination of propofol, fentanyl, and midazolam received the least amount of propofol and required the least time to recover. There were no life-threatening complications. Conclusions: Propofol-based anesthesia, when administered by an anesthesiologist in a controlled setting, is safe and effective for performing painful procedures in children with cancer.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 04/04/20 alle ore 12:04:31