Catalogo Articoli (Spogli Riviste)

OPAC HELP

Titolo:
Involvement of human amygdala and orbitofrontal cortex in hunger-enhanced memory for food stimuli
Autore:
Morris, JS; Dolan, RJ;
Indirizzi:
Wellcome Dept Cognit Neurol, London WC1N 3BG, England Wellcome Dept CognitNeurol London England WC1N 3BG on WC1N 3BG, England Inst Cognit Neurosci, London WC1N 3AR, England Inst Cognit Neurosci London England WC1N 3AR i, London WC1N 3AR, England Inst Child Hlth, London WC1N 1EH, England Inst Child Hlth London EnglandWC1N 1EH d Hlth, London WC1N 1EH, England Royal Free & Univ Coll Hosp Sch Med, London NW3 2DF, England Royal Free & Univ Coll Hosp Sch Med London England NW3 2DF 2DF, England
Titolo Testata:
JOURNAL OF NEUROSCIENCE
fascicolo: 14, volume: 21, anno: 2001,
pagine: 5304 - 5310
SICI:
0270-6474(20010715)21:14<5304:IOHAAO>2.0.ZU;2-X
Fonte:
ISI
Lingua:
ENG
Soggetto:
PREFRONTAL CORTEX; NUCLEUS-ACCUMBENS; BASOLATERAL AMYGDALA; DECLARATIVE MEMORY; VISUAL RECOGNITION; RHESUS-MONKEYS; SINGLE NEURONS; MACAQUE MONKEY; ALERT MONKEY; RESPONSES;
Keywords:
amygdala; orbitofrontal cortex; memory; food; hunger; satiety; functional neuroimaging;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Life Sciences
Citazioni:
39
Recensione:
Indirizzi per estratti:
Indirizzo: Dolan, RJ Wellcome Dept Cognit Neurol, 12 Queen Sq, London WC1N 3BG, England Wellcome Dept Cognit Neurol 12 Queen Sq London England WC1N 3BG
Citazione:
J.S. Morris e R.J. Dolan, "Involvement of human amygdala and orbitofrontal cortex in hunger-enhanced memory for food stimuli", J NEUROSC, 21(14), 2001, pp. 5304-5310

Abstract

We used positron emission tomography to measure regional cerebral blood flow (rCBF) in 10 healthy volunteers performing a recognition memory task with food and non-food items, The biological salience of the food stimuli was manipulated by requiring subjects to fast before the experiment and eat to satiation at fixed time points during scanning. All subjects showed enhanced recognition of food stimuli (relative to nonfood) in the fasting state. Satiation significantly reduced the memory advantage for food. Left amygdalarCBF covaried positively with recognition memory for food items, whereas rCBF in right anterior orbitofrontal cortex covaried with overall memory performance. Right posterior orbitofrontal rCBF covaried positively with hunger ratings during presentation of food items. Regression analysis of the neuroimaging data revealed that left amygdala and right lateral orbitofrontal rCBF covaried as a function of stimulus category (i.e,, food vs non-food). These results indicate the involvement of amygdala and discrete regions of orbitofrontal cortex in the integration of perceptual (food), motivational (hunger), and cognitive (memory) processes in the human brain.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 25/01/20 alle ore 06:46:35