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Titolo:
Lobular carcinoma in situ and infiltrating ductal carcinoma: Frequent presence of DCIS as a precursor lesion
Autore:
Maluf, H; Koerner, F;
Indirizzi:
Washington Univ, Sch Med, Dept Pathol & Immunol, St Louis, MO USA Washington Univ St Louis MO USA Dept Pathol & Immunol, St Louis, MO USA Massachusetts Gen Hosp, Dept Pathol, Boston, MA 02114 USA Massachusetts Gen Hosp Boston MA USA 02114 t Pathol, Boston, MA 02114 USA
Titolo Testata:
INTERNATIONAL JOURNAL OF SURGICAL PATHOLOGY
fascicolo: 2, volume: 9, anno: 2001,
pagine: 127 - 131
SICI:
1066-8969(200104)9:2<127:LCISAI>2.0.ZU;2-9
Fonte:
ISI
Lingua:
ENG
Soggetto:
E-CADHERIN EXPRESSION; IN-SITU; BREAST-CANCER; INVASIVE CANCER; PROSPECTIVE NATIONWIDE; CHROMOSOME 11Q13; FEMALE BREAST; FOLLOW-UP; INSITU; HETEROZYGOSITY;
Keywords:
lobular carcinoma in situ; ductal carcinoma in situ; infiltrating ductal carcinoma; E-cadherin; tubular carcinoma;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
30
Recensione:
Indirizzi per estratti:
Indirizzo: Maluf, H Washington Univ, Sch Med, Dept Pathol, Div Surg Pathol, 660 S Euclid Ave,Box 8118, St Louis, MO 63110 USA Washington Univ 660 S Euclid Ave,Box 8118 St Louis MO USA 63110 A
Citazione:
H. Maluf e F. Koerner, "Lobular carcinoma in situ and infiltrating ductal carcinoma: Frequent presence of DCIS as a precursor lesion", INT J SUR P, 9(2), 2001, pp. 127-131

Abstract

Infiltrating ductal carcinoma (IDC) occurs frequently in patients with lobular carcinoma in-situ (LCIS). LCIS is not thought to be the direct precursor of the invasive component. The authors analyzed 15 cases of coexisting LCIS and IDC and found ductal carcinoma in situ (DCIS) in 12. The DCIS and IDC were of similar grade and located in the same area. Selected cases stained with E-cadherin demonstrated a different immunophenotype for the lobularand ductal lesions. These results support the notion that DCIS is the direct precursor of IDC occurring in patients with LCIS.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 08/04/20 alle ore 23:59:24