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Titolo:
Enhanced stress reactivity in paediatric anxiety disorders: implications for future cardiovascular health
Autore:
Monk, C; Kovelenko, P; Ellman, LM; Sloan, RP; Bagiella, E; Gorman, JM; Pine, DS;
Indirizzi:
New York State Psychiat Inst, Unit 40, Dept Child & Adolescent Psychiat, New York, NY 10032 USA New York State Psychiat Inst New York NY USA 10032 New York, NY 10032 USA Columbia Univ, Coll Phys & Surg, New York, NY USA Columbia Univ New York NY USA a Univ, Coll Phys & Surg, New York, NY USA
Titolo Testata:
INTERNATIONAL JOURNAL OF NEUROPSYCHOPHARMACOLOGY
fascicolo: 2, volume: 4, anno: 2001,
pagine: 199 - 206
SICI:
1461-1457(200106)4:2<199:ESRIPA>2.0.ZU;2-8
Fonte:
ISI
Lingua:
ENG
Soggetto:
HEART-RATE-VARIABILITY; CORONARY-ARTERY DISEASE; ACUTE MYOCARDIAL-INFARCTION; CARDIAC AUTONOMIC CONTROL; POWER SPECTRAL-ANALYSIS; LONG-TERM MORTALITY; PANIC DISORDER; BEHAVIORAL-INHIBITION; MAJOR DEPRESSION; ADOLESCENT MALES;
Keywords:
paediatric anxiety disorders; cardiovascular disease; stress; heart rate; heart rate variability;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Clinical Medicine
Citazioni:
66
Recensione:
Indirizzi per estratti:
Indirizzo: Monk, C New York State Psychiat Inst, Unit 40, Dept Child & Adolescent Psychiat, New York, NY 10032 USA New York State Psychiat Inst New York NY USA10032 , NY 10032 USA
Citazione:
C. Monk et al., "Enhanced stress reactivity in paediatric anxiety disorders: implications for future cardiovascular health", IN J NEUROP, 4(2), 2001, pp. 199-206

Abstract

The aim was to clarify the developmental nature of associations between psychiatric illness and risk for cardiovascular disease by investigating differences in cardiac functioning between youth with anxiety disorders and healthy controls. Twenty-two children meeting DSM-IV criteria for either separation anxiety disorder, overanxious disorder. panic disorder/panic attacks.or social phobia and 12 healthy controls underwent continuous electrocardiogram and respiration rate monitoring during a 15 min baseline period and 15 min of exposure to 5 % CO2. Heart rate (HR) and high frequency heart ratevariability (HRV), a non-invasive measure of cardiac parasympathetic control, were calculated. Youth with anxiety disorders had higher and less fluctuating HR during baseline. Data also suggested that probands showed diminished overall changes in HRV during baseline and CO2 inhalation relative to controls. However, as respiration rate affects HRV, these findings were confounded by changes in respiration elicited by CO2 inhalation. The data suggest that youth with anxiety disorders experience an elevated and less fluctuating HX in the face of a novel situation, possibly due to a failure to appropriately modulate HRV. In adults, sustained elevations in HR in conjunction with deficient vagal modulation predicts risk for future cardiovascular disease. As such, the current data suggest that the presence of an anxiety disorder may identify youth who exhibit autonomic profiles that place them at risk for cardiac disease.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 27/01/20 alle ore 14:53:02