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Titolo: PKC in eggs and embryos
Autore: Eliyahu, E; Kaplan-Kraicer, R; Shalgi, R;
- Indirizzi:
- Tel Aviv Univ, Sackler Fac Med, Dept Embryol, IL-69978 Tel Aviv, Israel Tel Aviv Univ Tel Aviv Israel IL-69978 mbryol, IL-69978 Tel Aviv, Israel
- Titolo Testata:
- FRONTIERS IN BIOSCIENCE
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volume: 6,
anno: 2001,
pagine: D785 - D791
- SICI:
- 1093-9946(200107)6:<D785:PIEAE>2.0.ZU;2-X
- Fonte:
- ISI
- Lingua:
- ENG
- Soggetto:
- PROTEIN-KINASE-C; CORTICAL GRANULE EXOCYTOSIS; REPETITIVE CALCIUM TRANSIENTS; CELL-CYCLE ACTIVATION; MOUSE EGGS; PHORBOL ESTER; INOSITOL 1,4,5-TRISPHOSPHATE; MAMMALIAN EGG; ZONA-PELLUCIDA; CA2+ RELEASE;
- Keywords:
- PKC; egg; activation; fertilization; review;
- Tipo documento:
- Article
- Natura:
- Periodico
- Settore Disciplinare:
- Life Sciences
- Citazioni:
- 72
- Recensione:
- Indirizzi per estratti:
- Indirizzo: Shalgi, R Tel Aviv Univ, Sackler Fac Med, Dept Embryol, IL-69978 Tel Aviv,Israel Tel Aviv Univ Tel Aviv Israel IL-69978 -69978 Tel Aviv, Israel
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- Citazione:
- E. Eliyahu et al., "PKC in eggs and embryos", FRONT BIOSC, 6, 2001, pp. D785-D791
Abstract
After a spermatozoon enters the egg, rapid processes such as the cortical granules exocytosis (CGE) occur. Other, later processes are observed as well, and they include resumption of the second meiotic division, second polarbody (PBII) extrusion and rearrangement of the DNA inside the pronuclei (PN). The above mentioned biochemical processes involve signal transduction pathways that are well known in other cell systems, and require mediation ofsecond messengers like Ca2+ and diacylglycerol (DAG) which are protein kinase C (PKC) activators. The present review, based upon recently published studies, raises the possibility of PKC involvement in fertilization and in early developmental stages of the mammalian embryo.
ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 20/01/21 alle ore 01:33:22