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Titolo:
Comparison of the thermodynamic properties of structurally related amphiphilic antidepressants in aqueous solution
Autore:
Taboada, P; Ruso, JM; Garcia, M; Mosquera, V;
Indirizzi:
Univ Santiago de Compostela, Dept Fis Mat Condensada, Grp Fis Coloides & Polimeros, E-15706 Santiago De Compostela, Spain Univ Santiago de Compostela Santiago De Compostela Spain E-15706 , Spain Univ Santiago de Compostela, Fac Fis, Dept Fis Aplicada, E-15706 Santiago De Compostela, Spain Univ Santiago de Compostela Santiago De Compostela Spain E-15706 , Spain
Titolo Testata:
COLLOID AND POLYMER SCIENCE
fascicolo: 7, volume: 279, anno: 2001,
pagine: 716 - 720
SICI:
0303-402X(200107)279:7<716:COTTPO>2.0.ZU;2-Y
Fonte:
ISI
Lingua:
ENG
Soggetto:
SELF-ASSOCIATION; ACTIVITY-COEFFICIENTS; PHENOTHIAZINE DRUGS; MICELLE FORMATION; LIGHT-SCATTERING; AGGREGATION; DEPENDENCE;
Keywords:
amitriptyline; desipramine; nortriptyline; critical micelle concentration; thermodynamic parameters;
Tipo documento:
Article
Natura:
Periodico
Settore Disciplinare:
Physical, Chemical & Earth Sciences
Citazioni:
20
Recensione:
Indirizzi per estratti:
Indirizzo: Mosquera, V Univ Santiago de Compostela, Dept Fis Mat Condensada, Grp Fis Coloides & Polimeros, E-15706 Santiago De Compostela, Spain Univ Santiago de Compostela Santiago De Compostela Spain E-15706
Citazione:
P. Taboada et al., "Comparison of the thermodynamic properties of structurally related amphiphilic antidepressants in aqueous solution", COLLOID P S, 279(7), 2001, pp. 716-720

Abstract

The critical concentrations of amitriptyline, desipramine and nortriptyline hydrochlorides in aqueous solution were determined over the temperature range 288-313 K by a method based on deconvolution into Gaussians of the second derivate of the measured specific conductivity data. The mass-action model was used to calculate the thermodynamic quantities: standard free Gibbsenergy, standard enthalpy and standard entropy of aggregate formation. Theresults are discussed in terms of the structure of the drug aggregates.

ASDD Area Sistemi Dipartimentali e Documentali, Università di Bologna, Catalogo delle riviste ed altri periodici
Documento generato il 02/04/20 alle ore 12:54:26